Molecular docking analysis of penta galloyl glucose with the bcl-2 family of anti-apoptotic targets

Apoptosis requires cellular proteins from the B-cell lymphoma 2 (BCL-2) family linked to breast cancer. Therefore, it is of interest to document the Molecular docking analysis data of penta galloyl glucose with the bcl-2 family of anti-apoptotic targets (Bcl-2, BCL-XL, Caspase 3, and Caspase 9). Dat...

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Detalles Bibliográficos
Autores principales: Dharmalingam, Karthick, Dharmalingam, Velvizhi, Durairaj, Satheesh, Sharma, Praveen, Jayaraman, Selvaraj, Choudhary, Sarita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9070626/
https://www.ncbi.nlm.nih.gov/pubmed/35574508
http://dx.doi.org/10.6026/97320630017861
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author Dharmalingam, Karthick
Dharmalingam, Velvizhi
Durairaj, Satheesh
Sharma, Praveen
Jayaraman, Selvaraj
Choudhary, Sarita
author_facet Dharmalingam, Karthick
Dharmalingam, Velvizhi
Durairaj, Satheesh
Sharma, Praveen
Jayaraman, Selvaraj
Choudhary, Sarita
author_sort Dharmalingam, Karthick
collection PubMed
description Apoptosis requires cellular proteins from the B-cell lymphoma 2 (BCL-2) family linked to breast cancer. Therefore, it is of interest to document the Molecular docking analysis data of penta galloyl glucose with the bcl-2 family of anti-apoptotic targets (Bcl-2, BCL-XL, Caspase 3, and Caspase 9). Data shows that Pentagalloyl glucose have optimal binding features with Bcl-2, BCL-XL, Caspase 3, and Caspase 9 proteins with binding energy of -8.6,-7,-7.5 and 4.4 kcal/mol respectively for further consideration in this context.
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spelling pubmed-90706262022-05-12 Molecular docking analysis of penta galloyl glucose with the bcl-2 family of anti-apoptotic targets Dharmalingam, Karthick Dharmalingam, Velvizhi Durairaj, Satheesh Sharma, Praveen Jayaraman, Selvaraj Choudhary, Sarita Bioinformation Research Article Apoptosis requires cellular proteins from the B-cell lymphoma 2 (BCL-2) family linked to breast cancer. Therefore, it is of interest to document the Molecular docking analysis data of penta galloyl glucose with the bcl-2 family of anti-apoptotic targets (Bcl-2, BCL-XL, Caspase 3, and Caspase 9). Data shows that Pentagalloyl glucose have optimal binding features with Bcl-2, BCL-XL, Caspase 3, and Caspase 9 proteins with binding energy of -8.6,-7,-7.5 and 4.4 kcal/mol respectively for further consideration in this context. Biomedical Informatics 2021-10-31 /pmc/articles/PMC9070626/ /pubmed/35574508 http://dx.doi.org/10.6026/97320630017861 Text en © 2021 Biomedical Informatics https://creativecommons.org/licenses/by/3.0/This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
spellingShingle Research Article
Dharmalingam, Karthick
Dharmalingam, Velvizhi
Durairaj, Satheesh
Sharma, Praveen
Jayaraman, Selvaraj
Choudhary, Sarita
Molecular docking analysis of penta galloyl glucose with the bcl-2 family of anti-apoptotic targets
title Molecular docking analysis of penta galloyl glucose with the bcl-2 family of anti-apoptotic targets
title_full Molecular docking analysis of penta galloyl glucose with the bcl-2 family of anti-apoptotic targets
title_fullStr Molecular docking analysis of penta galloyl glucose with the bcl-2 family of anti-apoptotic targets
title_full_unstemmed Molecular docking analysis of penta galloyl glucose with the bcl-2 family of anti-apoptotic targets
title_short Molecular docking analysis of penta galloyl glucose with the bcl-2 family of anti-apoptotic targets
title_sort molecular docking analysis of penta galloyl glucose with the bcl-2 family of anti-apoptotic targets
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9070626/
https://www.ncbi.nlm.nih.gov/pubmed/35574508
http://dx.doi.org/10.6026/97320630017861
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