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Low Complexity Regions in Mammalian Proteins are Associated with Low Protein Abundance and High Transcript Abundance
Low Complexity Regions (LCRs) are present in a surprisingly large number of eukaryotic proteins. These highly repetitive and compositionally biased sequences are often structurally disordered, bind promiscuously, and evolve rapidly. Frequently studied in terms of evolutionary dynamics, little is kno...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9070799/ https://www.ncbi.nlm.nih.gov/pubmed/35482425 http://dx.doi.org/10.1093/molbev/msac087 |