Microwave-assisted iodine-catalyzed oxidative coupling of dibenzyl(difurfuryl)disulfides with amines: a rapid and efficient protocol for thioamides

An efficient protocol for synthesis of thioamides was developed via the microwave-assisted iodine-catalyzed oxidative coupling of dibenzyl(difurfuryl)disulfides with amines. This process is scalable and tolerates a wide spectrum of amines to deliver the corresponding products in moderate to excellen...

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Autores principales: Chen, Jinyang, Mei, Lan, Liu, Jialing, Zhong, Chuntao, Yuan, Binfang, Li, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9070997/
https://www.ncbi.nlm.nih.gov/pubmed/35529638
http://dx.doi.org/10.1039/c9ra05939c
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author Chen, Jinyang
Mei, Lan
Liu, Jialing
Zhong, Chuntao
Yuan, Binfang
Li, Qiang
author_facet Chen, Jinyang
Mei, Lan
Liu, Jialing
Zhong, Chuntao
Yuan, Binfang
Li, Qiang
author_sort Chen, Jinyang
collection PubMed
description An efficient protocol for synthesis of thioamides was developed via the microwave-assisted iodine-catalyzed oxidative coupling of dibenzyl(difurfuryl)disulfides with amines. This process is scalable and tolerates a wide spectrum of amines to deliver the corresponding products in moderate to excellent yields in 10 minutes, providing a cheap and rapid approach to thioamides.
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spelling pubmed-90709972022-05-06 Microwave-assisted iodine-catalyzed oxidative coupling of dibenzyl(difurfuryl)disulfides with amines: a rapid and efficient protocol for thioamides Chen, Jinyang Mei, Lan Liu, Jialing Zhong, Chuntao Yuan, Binfang Li, Qiang RSC Adv Chemistry An efficient protocol for synthesis of thioamides was developed via the microwave-assisted iodine-catalyzed oxidative coupling of dibenzyl(difurfuryl)disulfides with amines. This process is scalable and tolerates a wide spectrum of amines to deliver the corresponding products in moderate to excellent yields in 10 minutes, providing a cheap and rapid approach to thioamides. The Royal Society of Chemistry 2019-09-10 /pmc/articles/PMC9070997/ /pubmed/35529638 http://dx.doi.org/10.1039/c9ra05939c Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Chen, Jinyang
Mei, Lan
Liu, Jialing
Zhong, Chuntao
Yuan, Binfang
Li, Qiang
Microwave-assisted iodine-catalyzed oxidative coupling of dibenzyl(difurfuryl)disulfides with amines: a rapid and efficient protocol for thioamides
title Microwave-assisted iodine-catalyzed oxidative coupling of dibenzyl(difurfuryl)disulfides with amines: a rapid and efficient protocol for thioamides
title_full Microwave-assisted iodine-catalyzed oxidative coupling of dibenzyl(difurfuryl)disulfides with amines: a rapid and efficient protocol for thioamides
title_fullStr Microwave-assisted iodine-catalyzed oxidative coupling of dibenzyl(difurfuryl)disulfides with amines: a rapid and efficient protocol for thioamides
title_full_unstemmed Microwave-assisted iodine-catalyzed oxidative coupling of dibenzyl(difurfuryl)disulfides with amines: a rapid and efficient protocol for thioamides
title_short Microwave-assisted iodine-catalyzed oxidative coupling of dibenzyl(difurfuryl)disulfides with amines: a rapid and efficient protocol for thioamides
title_sort microwave-assisted iodine-catalyzed oxidative coupling of dibenzyl(difurfuryl)disulfides with amines: a rapid and efficient protocol for thioamides
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9070997/
https://www.ncbi.nlm.nih.gov/pubmed/35529638
http://dx.doi.org/10.1039/c9ra05939c
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