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Facile synthetic approach towards vasorelaxant active 4-hydroxyquinazoline-4-carboxamides
A Facile synthetic approach is reported towards 4-hydroxyquinazoline-4-carboxamides 13a–i through ring expansion of 2,3-dioxoindoline-1-carboxamides 10a–c during secondary amine 11a–d nucleophilic reaction. Single crystal X-ray studies of 10c and 13d support the structures. Some of the synthesized q...
Autores principales: | Aziz, Marian N., Panda, Siva S., Shalaby, ElSayed M., Fawzy, Nehmedo G., Girgis, Adel S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071013/ https://www.ncbi.nlm.nih.gov/pubmed/35529643 http://dx.doi.org/10.1039/c9ra04321g |
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