Peptidoglycan pathways: there are still more!

The discovery of 3(rd) and 4(th) generations of currently existing classes of antibiotics has not hindered bacterial resistance, which is escalating at an alarming global level. This review follows WHO recommendations through implementing new criteria for newly discovered antibiotics. These recommen...

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Detalles Bibliográficos
Autores principales: Helal, Ahmed M., Sayed, Ahmed M., Omara, Mariam, Elsebaei, Mohamed M., Mayhoub, Abdelrahman S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071014/
https://www.ncbi.nlm.nih.gov/pubmed/35530449
http://dx.doi.org/10.1039/c9ra04518j
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author Helal, Ahmed M.
Sayed, Ahmed M.
Omara, Mariam
Elsebaei, Mohamed M.
Mayhoub, Abdelrahman S.
author_facet Helal, Ahmed M.
Sayed, Ahmed M.
Omara, Mariam
Elsebaei, Mohamed M.
Mayhoub, Abdelrahman S.
author_sort Helal, Ahmed M.
collection PubMed
description The discovery of 3(rd) and 4(th) generations of currently existing classes of antibiotics has not hindered bacterial resistance, which is escalating at an alarming global level. This review follows WHO recommendations through implementing new criteria for newly discovered antibiotics. These recommendations focus on abandoning old scaffolds and hitting new targets. In light of these recommendations, this review discusses seven bacterial proteins that no commercial antibiotics have targeted yet, alongside their reported chemical scaffolds.
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spelling pubmed-90710142022-05-06 Peptidoglycan pathways: there are still more! Helal, Ahmed M. Sayed, Ahmed M. Omara, Mariam Elsebaei, Mohamed M. Mayhoub, Abdelrahman S. RSC Adv Chemistry The discovery of 3(rd) and 4(th) generations of currently existing classes of antibiotics has not hindered bacterial resistance, which is escalating at an alarming global level. This review follows WHO recommendations through implementing new criteria for newly discovered antibiotics. These recommendations focus on abandoning old scaffolds and hitting new targets. In light of these recommendations, this review discusses seven bacterial proteins that no commercial antibiotics have targeted yet, alongside their reported chemical scaffolds. The Royal Society of Chemistry 2019-09-09 /pmc/articles/PMC9071014/ /pubmed/35530449 http://dx.doi.org/10.1039/c9ra04518j Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Helal, Ahmed M.
Sayed, Ahmed M.
Omara, Mariam
Elsebaei, Mohamed M.
Mayhoub, Abdelrahman S.
Peptidoglycan pathways: there are still more!
title Peptidoglycan pathways: there are still more!
title_full Peptidoglycan pathways: there are still more!
title_fullStr Peptidoglycan pathways: there are still more!
title_full_unstemmed Peptidoglycan pathways: there are still more!
title_short Peptidoglycan pathways: there are still more!
title_sort peptidoglycan pathways: there are still more!
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071014/
https://www.ncbi.nlm.nih.gov/pubmed/35530449
http://dx.doi.org/10.1039/c9ra04518j
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AT elsebaeimohamedm peptidoglycanpathwaystherearestillmore
AT mayhoubabdelrahmans peptidoglycanpathwaystherearestillmore

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