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A matching algorithm with isotope distribution pattern in LC-MS based on support vector machine (SVM) learning model

In proteomics, it is important to detect, analyze, and quantify complex peptide components and differences. The key is to match the elution time peaks (LC peaks) produced by the same peptide in replicate experiments. Warping functions are currently widely used to correct the mean of time shifts amon...

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Detalles Bibliográficos
Autores principales: Cui, Jian, Chen, Qiang, Dong, Xiaorui, Shang, Kai, Qi, Xin, Cui, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071103/
https://www.ncbi.nlm.nih.gov/pubmed/35530479
http://dx.doi.org/10.1039/c9ra03789f