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Blockade of p38 MAPK overcomes AML stem cell line KG1a resistance to 5-Fluorouridine and the impact on miRNA profiling

Most of the AML patients in remission develop multidrug resistance after the first-line therapy and relapse. AML stem cells have gained attention for their chemoresistance potentials. Chemoresistance is a multifactorial process resulting from altered survival signaling pathways and apoptosis regulat...

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Detalles Bibliográficos
Autores principales:	Matou-Nasri, Sabine, Najdi, Maria, AlSaud, Nouran Abu, Alhaidan, Yazeid, Al-Eidi, Hamad, Alatar, Ghada, AlWadaani, Deemah, Trivilegio, Thadeo, AlSubait, Arwa, AlTuwaijri, Abeer, Abudawood, Manal, Almuzzaini, Bader
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071118/ https://www.ncbi.nlm.nih.gov/pubmed/35511922 http://dx.doi.org/10.1371/journal.pone.0267855

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