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Comparison of conventional versus customised Eurosil-4 Pink bolus for radiotherapy of the chest wall

INTRODUCTION: In radiotherapy, the presence of air gaps near a tumour can lead to underdose to the tumour. In this study, the impact of air gaps on dose to the surface was evaluated. 3D-printing was used to construct a Eurosil-4 Pink bolus customised to the patient and its dosimetric properties were...

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Autores principales: Gill, Ashlesha, Smith, Warwick, Hirst, Andrew, Sabet, Mahsheed, Alkhatib, Zaid, Gill, Suki, Rowshanfarzad, Pejman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071134/
https://www.ncbi.nlm.nih.gov/pubmed/35511918
http://dx.doi.org/10.1371/journal.pone.0267741
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author Gill, Ashlesha
Smith, Warwick
Hirst, Andrew
Sabet, Mahsheed
Alkhatib, Zaid
Gill, Suki
Rowshanfarzad, Pejman
author_facet Gill, Ashlesha
Smith, Warwick
Hirst, Andrew
Sabet, Mahsheed
Alkhatib, Zaid
Gill, Suki
Rowshanfarzad, Pejman
author_sort Gill, Ashlesha
collection PubMed
description INTRODUCTION: In radiotherapy, the presence of air gaps near a tumour can lead to underdose to the tumour. In this study, the impact of air gaps on dose to the surface was evaluated. 3D-printing was used to construct a Eurosil-4 Pink bolus customised to the patient and its dosimetric properties were compared with that of Paraffin wax bolus. METHODS: Surface dose was measured for flat sheets of Eurosil-4 Pink bolus with different thicknesses. Different air gap thicknesses were inserted between the bolus and the surface, and dose was measured for each air gap using 10 cm × 10 cm fields. This was repeated with the effective field size calculated from the patient plan. Surface dose was measured for varying angles of incidence. A customised chest phantom was used to compare dose for two customised Eurosil-4 Pink boluses, and commonly used Paraffin wax bolus. RESULTS: The surface dose was found to be highest for 1.1 cm thick bolus. The decrease in surface dose for the Eurosil-4 Pink bolus was minimal for the 10 cm × 10 cm field, but higher for the effective field size and larger angles of incidence. For instance, the dose was reduced by 6.2% as a result of 1 cm air gap for the effective field size and 60 degree angle of incidence. The doses measured using Gafchromic film under the customised Eurosil-4 Pink boluses were similar to that of the Paraffin wax bolus, and higher than prescribed dose. CONCLUSIONS: The impact of air gaps can be significant for small field sizes and oblique beams. A customised Eurosil-4 Pink bolus has promising physical and dosimetric properties to ensure sufficient dose to the tumour, even for treatments where larger impact of air gaps is suspected.
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spelling pubmed-90711342022-05-06 Comparison of conventional versus customised Eurosil-4 Pink bolus for radiotherapy of the chest wall Gill, Ashlesha Smith, Warwick Hirst, Andrew Sabet, Mahsheed Alkhatib, Zaid Gill, Suki Rowshanfarzad, Pejman PLoS One Research Article INTRODUCTION: In radiotherapy, the presence of air gaps near a tumour can lead to underdose to the tumour. In this study, the impact of air gaps on dose to the surface was evaluated. 3D-printing was used to construct a Eurosil-4 Pink bolus customised to the patient and its dosimetric properties were compared with that of Paraffin wax bolus. METHODS: Surface dose was measured for flat sheets of Eurosil-4 Pink bolus with different thicknesses. Different air gap thicknesses were inserted between the bolus and the surface, and dose was measured for each air gap using 10 cm × 10 cm fields. This was repeated with the effective field size calculated from the patient plan. Surface dose was measured for varying angles of incidence. A customised chest phantom was used to compare dose for two customised Eurosil-4 Pink boluses, and commonly used Paraffin wax bolus. RESULTS: The surface dose was found to be highest for 1.1 cm thick bolus. The decrease in surface dose for the Eurosil-4 Pink bolus was minimal for the 10 cm × 10 cm field, but higher for the effective field size and larger angles of incidence. For instance, the dose was reduced by 6.2% as a result of 1 cm air gap for the effective field size and 60 degree angle of incidence. The doses measured using Gafchromic film under the customised Eurosil-4 Pink boluses were similar to that of the Paraffin wax bolus, and higher than prescribed dose. CONCLUSIONS: The impact of air gaps can be significant for small field sizes and oblique beams. A customised Eurosil-4 Pink bolus has promising physical and dosimetric properties to ensure sufficient dose to the tumour, even for treatments where larger impact of air gaps is suspected. Public Library of Science 2022-05-05 /pmc/articles/PMC9071134/ /pubmed/35511918 http://dx.doi.org/10.1371/journal.pone.0267741 Text en https://creativecommons.org/publicdomain/zero/1.0/This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 (https://creativecommons.org/publicdomain/zero/1.0/) public domain dedication.
spellingShingle Research Article
Gill, Ashlesha
Smith, Warwick
Hirst, Andrew
Sabet, Mahsheed
Alkhatib, Zaid
Gill, Suki
Rowshanfarzad, Pejman
Comparison of conventional versus customised Eurosil-4 Pink bolus for radiotherapy of the chest wall
title Comparison of conventional versus customised Eurosil-4 Pink bolus for radiotherapy of the chest wall
title_full Comparison of conventional versus customised Eurosil-4 Pink bolus for radiotherapy of the chest wall
title_fullStr Comparison of conventional versus customised Eurosil-4 Pink bolus for radiotherapy of the chest wall
title_full_unstemmed Comparison of conventional versus customised Eurosil-4 Pink bolus for radiotherapy of the chest wall
title_short Comparison of conventional versus customised Eurosil-4 Pink bolus for radiotherapy of the chest wall
title_sort comparison of conventional versus customised eurosil-4 pink bolus for radiotherapy of the chest wall
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071134/
https://www.ncbi.nlm.nih.gov/pubmed/35511918
http://dx.doi.org/10.1371/journal.pone.0267741
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