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Enhanced stability of an intrinsically disordered protein against proteolytic cleavage through interactions with silver nanoparticles

Intrinsically disordered proteins (IDPs), being sensitive to proteolytic degradation both in vitro and in vivo, can be stabilized by the interactions with various binding partners. Here, we show for the first time that silver nanoparticles (AgNPs) have the ability to enhance the half-life of an IDP,...

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Detalles Bibliográficos
Autores principales: Malik, Shahid A., Mondal, Somnath, Atreya, Hanudatta S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071183/
https://www.ncbi.nlm.nih.gov/pubmed/35529627
http://dx.doi.org/10.1039/c9ra05514b