N-Heterocyclic carbene copper catalyzed quinoline synthesis from 2-aminobenzyl alcohols and ketones using DMSO as an oxidant at room temperature

A facile and practical process for the synthesis of quinolines through an N-heterocyclic carbene copper catalyzed indirect Friedländer reaction from 2-aminobenzyl alcohol and aryl ketones using DMSO as an oxidant at room temperature is reported. A series of quinolines were synthesized in acceptable...

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Autores principales: Xu, Jingxiu, Chen, Qingmao, Luo, Zhigao, Tang, Xiaodong, Zhao, Jinwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071191/
https://www.ncbi.nlm.nih.gov/pubmed/35529656
http://dx.doi.org/10.1039/c9ra04926f
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author Xu, Jingxiu
Chen, Qingmao
Luo, Zhigao
Tang, Xiaodong
Zhao, Jinwu
author_facet Xu, Jingxiu
Chen, Qingmao
Luo, Zhigao
Tang, Xiaodong
Zhao, Jinwu
author_sort Xu, Jingxiu
collection PubMed
description A facile and practical process for the synthesis of quinolines through an N-heterocyclic carbene copper catalyzed indirect Friedländer reaction from 2-aminobenzyl alcohol and aryl ketones using DMSO as an oxidant at room temperature is reported. A series of quinolines were synthesized in acceptable yields.
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spelling pubmed-90711912022-05-06 N-Heterocyclic carbene copper catalyzed quinoline synthesis from 2-aminobenzyl alcohols and ketones using DMSO as an oxidant at room temperature Xu, Jingxiu Chen, Qingmao Luo, Zhigao Tang, Xiaodong Zhao, Jinwu RSC Adv Chemistry A facile and practical process for the synthesis of quinolines through an N-heterocyclic carbene copper catalyzed indirect Friedländer reaction from 2-aminobenzyl alcohol and aryl ketones using DMSO as an oxidant at room temperature is reported. A series of quinolines were synthesized in acceptable yields. The Royal Society of Chemistry 2019-09-12 /pmc/articles/PMC9071191/ /pubmed/35529656 http://dx.doi.org/10.1039/c9ra04926f Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Xu, Jingxiu
Chen, Qingmao
Luo, Zhigao
Tang, Xiaodong
Zhao, Jinwu
N-Heterocyclic carbene copper catalyzed quinoline synthesis from 2-aminobenzyl alcohols and ketones using DMSO as an oxidant at room temperature
title N-Heterocyclic carbene copper catalyzed quinoline synthesis from 2-aminobenzyl alcohols and ketones using DMSO as an oxidant at room temperature
title_full N-Heterocyclic carbene copper catalyzed quinoline synthesis from 2-aminobenzyl alcohols and ketones using DMSO as an oxidant at room temperature
title_fullStr N-Heterocyclic carbene copper catalyzed quinoline synthesis from 2-aminobenzyl alcohols and ketones using DMSO as an oxidant at room temperature
title_full_unstemmed N-Heterocyclic carbene copper catalyzed quinoline synthesis from 2-aminobenzyl alcohols and ketones using DMSO as an oxidant at room temperature
title_short N-Heterocyclic carbene copper catalyzed quinoline synthesis from 2-aminobenzyl alcohols and ketones using DMSO as an oxidant at room temperature
title_sort n-heterocyclic carbene copper catalyzed quinoline synthesis from 2-aminobenzyl alcohols and ketones using dmso as an oxidant at room temperature
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071191/
https://www.ncbi.nlm.nih.gov/pubmed/35529656
http://dx.doi.org/10.1039/c9ra04926f
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