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Endothelial SIRPα signaling controls VE-cadherin endocytosis for thymic homing of progenitor cells

Thymic homing of hematopoietic progenitor cells (HPCs) is tightly regulated for proper T cell development. Previously we have identified a subset of specialized thymic portal endothelial cells (TPECs), which is important for thymic HPC homing. However, the underlying molecular mechanism still remain...

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Detalles Bibliográficos
Autores principales:	Ren, Boyang, Xia, Huan, Liao, Yijun, Zhou, Hang, Wang, Zhongnan, Shi, Yaoyao, Zhu, Mingzhao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2022
Materias:	Immunology and Inflammation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071265/ https://www.ncbi.nlm.nih.gov/pubmed/35511221 http://dx.doi.org/10.7554/eLife.69219

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