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Development of a Novel Assay to Assess the Avidity of Dengue Virus-Specific Antibodies Elicited in Response to a Tetravalent Dengue Vaccine

Antibody affinity maturation is a critical step in development of functional antiviral immunity; however, accurate measurement of affinity maturation of polyclonal serum antibody responses to particulate antigens such as virions is challenging. We describe a novel avidity assay employing biolayer in...

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Detalles Bibliográficos
Autores principales: Tsuji, Isamu, Dominguez, David, Egan, Michael A, Dean, Hansi J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071338/
https://www.ncbi.nlm.nih.gov/pubmed/33534885
http://dx.doi.org/10.1093/infdis/jiab064