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Development of a Novel Assay to Assess the Avidity of Dengue Virus-Specific Antibodies Elicited in Response to a Tetravalent Dengue Vaccine
Antibody affinity maturation is a critical step in development of functional antiviral immunity; however, accurate measurement of affinity maturation of polyclonal serum antibody responses to particulate antigens such as virions is challenging. We describe a novel avidity assay employing biolayer in...
Autores principales: | Tsuji, Isamu, Dominguez, David, Egan, Michael A, Dean, Hansi J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071338/ https://www.ncbi.nlm.nih.gov/pubmed/33534885 http://dx.doi.org/10.1093/infdis/jiab064 |
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