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Olaparib in patients with mCRPC with homologous recombination repair gene alterations: PROfound Asian subset analysis
BACKGROUND: The Phase III PROfound study (NCT02987543) evaluated olaparib versus abiraterone or enzalutamide (control; randomized 2:1 to olaparib or control) in men with homologous recombination repair gene alterations and metastatic castration-resistant prostate cancer whose disease progressed on p...
Autores principales: | Matsubara, Nobuaki, Nishimura, Kazuo, Kawakami, Satoru, Joung, Jae Young, Uemura, Hiroji, Goto, Takayuki, Kwon, Tae Gyun, Sugimoto, Mikio, Kato, Masashi, Wang, Shian-Shiang, Pang, See-Tong, Chen, Chung-Hsin, Fujita, Tomoko, Nii, Masahiro, Shen, Liji, Dujka, Melanie, Hussain, Maha, de Bono, Johann |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071396/ https://www.ncbi.nlm.nih.gov/pubmed/35229141 http://dx.doi.org/10.1093/jjco/hyac015 |
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