Histone H3.3 phosphorylation promotes heterochromatin formation by inhibiting H3K9/K36 histone demethylase

Histone H3.3 is an H3 variant which differs from the canonical H3.1/2 at four residues, including a serine residue at position 31 which is evolutionarily conserved. The H3.3 S31 residue is phosphorylated (H3.3 S31Ph) at heterochromatin regions including telomeres and pericentric repeats. However, th...

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Detalles Bibliográficos
Autores principales: Udugama, Maheshi, Vinod, Benjamin, Chan, F Lyn, Hii, Linda, Garvie, Andrew, Collas, Philippe, Kalitsis, Paul, Steer, David, Das, Partha P, Tripathi, Pratibha, Mann, Jeffrey R, Voon, Hsiao P J, Wong, Lee H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071403/
https://www.ncbi.nlm.nih.gov/pubmed/35451487
http://dx.doi.org/10.1093/nar/gkac259

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