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Microarray screening reveals two non-conventional SUMO-binding modules linked to DNA repair by non-homologous end-joining

SUMOylation is critical for numerous cellular signalling pathways, including the maintenance of genome integrity via the repair of DNA double-strand breaks (DSBs). If misrepaired, DSBs can lead to cancer, neurodegeneration, immunodeficiency and premature ageing. Using systematic human proteome micro...

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Detalles Bibliográficos
Autores principales:	Cabello-Lobato, Maria Jose, Jenner, Matthew, Cisneros-Aguirre, Metztli, Brüninghoff, Kira, Sandy, Zac, da Costa, Isabelle C, Jowitt, Thomas A, Loch, Christian M, Jackson, Stephen P, Wu, Qian, Mootz, Henning D, Stark, Jeremy M, Cliff, Matthew J, Schmidt, Christine K
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071424/ https://www.ncbi.nlm.nih.gov/pubmed/35420136 http://dx.doi.org/10.1093/nar/gkac237

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