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Dorsal telencephalon-specific Nprl2- and Nprl3-knockout mice: novel mouse models for GATORopathy

The most frequent genetic cause of focal epilepsies is variations in the GAP activity toward RAGs 1 complex genes DEP domain containing 5 (DEPDC5), nitrogen permease regulator 2-like protein (NPRL2) and nitrogen permease regulator 3-like protein (NPRL3). Because these variations are frequent and ass...

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Detalles Bibliográficos
Autores principales:	Ishida, Saeko, Zhao, Di, Sawada, Yuta, Hiraoka, Yuichi, Mashimo, Tomoji, Tanaka, Kohichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	General Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071434/ https://www.ncbi.nlm.nih.gov/pubmed/34965576 http://dx.doi.org/10.1093/hmg/ddab337

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