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Rational design of self-assembled RNA nanostructures for HIV-1 virus assembly blockade
Many pathological processes are driven by RNA-protein interactions, making such interactions promising targets for molecular interventions. HIV-1 assembly is one such process, in which the viral genomic RNA interacts with the viral Gag protein and serves as a scaffold to drive Gag multimerization th...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071489/ https://www.ncbi.nlm.nih.gov/pubmed/34967412 http://dx.doi.org/10.1093/nar/gkab1282 |