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Serum interferon-α2 measured by single-molecule array associates with systemic disease manifestations in Sjögren’s syndrome

OBJECTIVES: Type I IFN (IFN-I) activation is a prominent feature of primary SS (pSS), SLE and SSc. Ultrasensitive single-molecule array (Simoa) technology has facilitated the measurement of subfemtomolar concentrations of IFNs. Here we aimed to measure IFN-α2 in serum from pSS, SLE and SSc using a S...

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Detalles Bibliográficos
Autores principales: Huijser, Erika, Göpfert, Jens, Brkic, Zana, van Helden-Meeuwsen, Cornelia G, Jansen, Sanne, Mandl, Thomas, Olsson, Peter, Schrijver, Benjamin, Schreurs, Marco W J, van Daele, Paul L A, Dik, Willem A, Versnel, Marjan A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071525/
https://www.ncbi.nlm.nih.gov/pubmed/34505866
http://dx.doi.org/10.1093/rheumatology/keab688