Cargando…
Serum interferon-α2 measured by single-molecule array associates with systemic disease manifestations in Sjögren’s syndrome
OBJECTIVES: Type I IFN (IFN-I) activation is a prominent feature of primary SS (pSS), SLE and SSc. Ultrasensitive single-molecule array (Simoa) technology has facilitated the measurement of subfemtomolar concentrations of IFNs. Here we aimed to measure IFN-α2 in serum from pSS, SLE and SSc using a S...
Autores principales: | Huijser, Erika, Göpfert, Jens, Brkic, Zana, van Helden-Meeuwsen, Cornelia G, Jansen, Sanne, Mandl, Thomas, Olsson, Peter, Schrijver, Benjamin, Schreurs, Marco W J, van Daele, Paul L A, Dik, Willem A, Versnel, Marjan A |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071525/ https://www.ncbi.nlm.nih.gov/pubmed/34505866 http://dx.doi.org/10.1093/rheumatology/keab688 |
Ejemplares similares
-
Hyperresponsive cytosolic DNA-sensing pathway in monocytes from primary Sjögren’s syndrome
por: Huijser, Erika, et al.
Publicado: (2022) -
MxA as a clinically applicable biomarker for identifying systemic interferon type I in primary Sjögren's syndrome
por: Maria, Naomi I, et al.
Publicado: (2014) -
Trained Immunity in Primary Sjögren’s Syndrome: Linking Type I Interferons to a Pro-Atherogenic Phenotype
por: Huijser, Erika, et al.
Publicado: (2022) -
Serum IFNα2 levels are associated with disease activity and outperform IFN-I gene signature in a longitudinal childhood-onset SLE cohort
por: Wahadat, M Javad, et al.
Publicado: (2022) -
Prevalence of interferon type I signature in CD14 monocytes of patients with Sjögren's syndrome and association with disease activity and BAFF gene expression
por: Brkic, Zana, et al.
Publicado: (2013)