2-deoxy-2[(18)F]fluoro-D-glucose positron emission tomography–computed tomography in rheumatological diseases

2-deoxy-2[(18)F]fluoro-D-glucose (FDG) PET-CT has revolutionized oncological imaging. The cellular processes that make cancer cells visible on FDG PET-CT also occur in a number of inflammatory cells. Exploiting this phenomenon has led to a growth of evidence supporting the use of FDG PET-CT in a wid...

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Autores principales: Subesinghe, Manil, Bhuva, Shaheel, Arumalla, Nikita, Cope, Andrew, D’Cruz, David, Subesinghe, Sujith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071551/
https://www.ncbi.nlm.nih.gov/pubmed/34463703
http://dx.doi.org/10.1093/rheumatology/keab675
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author Subesinghe, Manil
Bhuva, Shaheel
Arumalla, Nikita
Cope, Andrew
D’Cruz, David
Subesinghe, Sujith
author_facet Subesinghe, Manil
Bhuva, Shaheel
Arumalla, Nikita
Cope, Andrew
D’Cruz, David
Subesinghe, Sujith
author_sort Subesinghe, Manil
collection PubMed
description 2-deoxy-2[(18)F]fluoro-D-glucose (FDG) PET-CT has revolutionized oncological imaging. The cellular processes that make cancer cells visible on FDG PET-CT also occur in a number of inflammatory cells. Exploiting this phenomenon has led to a growth of evidence supporting the use of FDG PET-CT in a wide range of infective and inflammatory diseases. Rheumatological diseases can affect multiple sites within the musculoskeletal system alongside multi-organ extra-articular disease manifestations. Inflammation is central to these diseases, making FDG PET-CT a logical choice. In this review article we describe the various applications of FDG PET-CT in rheumatological diseases using illustrative examples to highlight the beneficial role of FDG PET-CT in each case.
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spelling pubmed-90715512022-05-06 2-deoxy-2[(18)F]fluoro-D-glucose positron emission tomography–computed tomography in rheumatological diseases Subesinghe, Manil Bhuva, Shaheel Arumalla, Nikita Cope, Andrew D’Cruz, David Subesinghe, Sujith Rheumatology (Oxford) Review Article 2-deoxy-2[(18)F]fluoro-D-glucose (FDG) PET-CT has revolutionized oncological imaging. The cellular processes that make cancer cells visible on FDG PET-CT also occur in a number of inflammatory cells. Exploiting this phenomenon has led to a growth of evidence supporting the use of FDG PET-CT in a wide range of infective and inflammatory diseases. Rheumatological diseases can affect multiple sites within the musculoskeletal system alongside multi-organ extra-articular disease manifestations. Inflammation is central to these diseases, making FDG PET-CT a logical choice. In this review article we describe the various applications of FDG PET-CT in rheumatological diseases using illustrative examples to highlight the beneficial role of FDG PET-CT in each case. Oxford University Press 2021-08-31 /pmc/articles/PMC9071551/ /pubmed/34463703 http://dx.doi.org/10.1093/rheumatology/keab675 Text en © The Author(s) 2021. Published by Oxford University Press on behalf of the British Society for Rheumatology. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Review Article
Subesinghe, Manil
Bhuva, Shaheel
Arumalla, Nikita
Cope, Andrew
D’Cruz, David
Subesinghe, Sujith
2-deoxy-2[(18)F]fluoro-D-glucose positron emission tomography–computed tomography in rheumatological diseases
title 2-deoxy-2[(18)F]fluoro-D-glucose positron emission tomography–computed tomography in rheumatological diseases
title_full 2-deoxy-2[(18)F]fluoro-D-glucose positron emission tomography–computed tomography in rheumatological diseases
title_fullStr 2-deoxy-2[(18)F]fluoro-D-glucose positron emission tomography–computed tomography in rheumatological diseases
title_full_unstemmed 2-deoxy-2[(18)F]fluoro-D-glucose positron emission tomography–computed tomography in rheumatological diseases
title_short 2-deoxy-2[(18)F]fluoro-D-glucose positron emission tomography–computed tomography in rheumatological diseases
title_sort 2-deoxy-2[(18)f]fluoro-d-glucose positron emission tomography–computed tomography in rheumatological diseases
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071551/
https://www.ncbi.nlm.nih.gov/pubmed/34463703
http://dx.doi.org/10.1093/rheumatology/keab675
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