Population genetics and microevolution of clinical Candida glabrata reveals recombinant sequence types and hyper-variation within mitochondrial genomes, virulence genes, and drug targets

Candida glabrata is the second most common etiological cause of worldwide systemic candidiasis in adult patients. Genome analysis of 68 isolates from 8 hospitals across Scotland, together with 83 global isolates, revealed insights into the population genetics and evolution of C. glabrata. Clinical i...

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Detalles Bibliográficos
Autores principales: Helmstetter, Nicolas, Chybowska, Aleksandra D, Delaney, Christopher, Da Silva Dantas, Alessandra, Gifford, Hugh, Wacker, Theresa, Munro, Carol, Warris, Adilia, Jones, Brian, Cuomo, Christina A, Wilson, Duncan, Ramage, Gordon, Farrer, Rhys A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071574/
https://www.ncbi.nlm.nih.gov/pubmed/35199143
http://dx.doi.org/10.1093/genetics/iyac031

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