Synthesis and biological evaluation of potent benzoselenophene and heteroaromatic analogues of (S)-1-(chloromethyl)-8-methoxy-2,3-dihydro-1H-benzo[e]indol-5-ol (seco-MCBI)

A diverse series of compounds (18a–x) were synthesized from (S)-1-(chloromethyl)-8-methoxy-2,3-dihydro-1H-benzo[e]indol-5-ol (seco-MCBI) and benzoselenophene or heteroaromatic acids. These new compounds were evaluated for their cytotoxicity against the human gastric NCI-N87 and human ovarian SK-OV3...

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Detalles Bibliográficos
Autores principales: Mhetre, Amol B., Sreedhar, Eppakayala, Dubey, Rashmi, Sable, Ganesh A., Lee, Hangeun, Yang, Heekyoung, Lee, Kyoungmin, Nam, Do-Hyun, Lim, Dongyeol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071829/
https://www.ncbi.nlm.nih.gov/pubmed/35528410
http://dx.doi.org/10.1039/c9ra04749b

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