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To beat the heat – engineering of the most thermostable pyruvate decarboxylase to date

Pyruvate decarboxylase (PDC) is a key enzyme for the production of ethanol at high temperatures and for cell-free butanol synthesis. Thermostable, organic solvent stable PDC was evolved from bacterial PDCs. The new variant shows >1500-fold-improved half-life at 75 °C and >5000-fold-increased h...

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Detalles Bibliográficos
Autores principales:	Sutiono, Samuel, Satzinger, Katharina, Pick, André, Carsten, Jörg, Sieber, Volker
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2019
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071941/ https://www.ncbi.nlm.nih.gov/pubmed/35531508 http://dx.doi.org/10.1039/c9ra06251c

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