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In vitro and in silico determination of glutaminyl cyclase inhibitors

Alzheimer's disease (AD) is the most common form of neurodegenerative disease currently. It is widely accepted that AD is characterized by the self-assembly of amyloid beta (Aβ) peptides. The human glutaminyl cyclase (hQC) enzyme is characterized by association with Aβ peptide generation. The d...

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Detalles Bibliográficos
Autores principales:	Tran, Phuong-Thao, Hoang, Van-Hai, Lee, Jeewoo, Hien, Tran Thi Thu, Tung, Nguyen Thanh, Ngo, Son Tung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2019
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071946/ https://www.ncbi.nlm.nih.gov/pubmed/35531555 http://dx.doi.org/10.1039/c9ra05763c

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