Oxidative cyanation of N-aryltetrahydroisoquinoline induced by visible light for the synthesis of α-aminonitrile using potassium thiocyanate as a “CN” agent

A novel method for the synthesis of α-aminonitrile through visible-light-induced oxidative cyanation of N-aryltetrahydroisoquinoline with potassium thiocyanate has been developed. The process does not require the use of a photocatalyst, transition metal reagent, strong oxidizing agent, or toxic cyan...

Descripción completa

Detalles Bibliográficos
Autores principales: Yi, Bing, Yan, Ning, Yi, Niannian, Xie, Yanjun, Wen, Xiaoyong, Au, Chak-Tong, Lan, Donghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071963/
https://www.ncbi.nlm.nih.gov/pubmed/35531501
http://dx.doi.org/10.1039/c9ra06120g
_version_ 1784700947237175296
author Yi, Bing
Yan, Ning
Yi, Niannian
Xie, Yanjun
Wen, Xiaoyong
Au, Chak-Tong
Lan, Donghui
author_facet Yi, Bing
Yan, Ning
Yi, Niannian
Xie, Yanjun
Wen, Xiaoyong
Au, Chak-Tong
Lan, Donghui
author_sort Yi, Bing
collection PubMed
description A novel method for the synthesis of α-aminonitrile through visible-light-induced oxidative cyanation of N-aryltetrahydroisoquinoline with potassium thiocyanate has been developed. The process does not require the use of a photocatalyst, transition metal reagent, strong oxidizing agent, or toxic cyano-containing compound, which makes the reaction simple and green.
format Online
Article
Text
id pubmed-9071963
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher The Royal Society of Chemistry
record_format MEDLINE/PubMed
spelling pubmed-90719632022-05-06 Oxidative cyanation of N-aryltetrahydroisoquinoline induced by visible light for the synthesis of α-aminonitrile using potassium thiocyanate as a “CN” agent Yi, Bing Yan, Ning Yi, Niannian Xie, Yanjun Wen, Xiaoyong Au, Chak-Tong Lan, Donghui RSC Adv Chemistry A novel method for the synthesis of α-aminonitrile through visible-light-induced oxidative cyanation of N-aryltetrahydroisoquinoline with potassium thiocyanate has been developed. The process does not require the use of a photocatalyst, transition metal reagent, strong oxidizing agent, or toxic cyano-containing compound, which makes the reaction simple and green. The Royal Society of Chemistry 2019-09-19 /pmc/articles/PMC9071963/ /pubmed/35531501 http://dx.doi.org/10.1039/c9ra06120g Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Yi, Bing
Yan, Ning
Yi, Niannian
Xie, Yanjun
Wen, Xiaoyong
Au, Chak-Tong
Lan, Donghui
Oxidative cyanation of N-aryltetrahydroisoquinoline induced by visible light for the synthesis of α-aminonitrile using potassium thiocyanate as a “CN” agent
title Oxidative cyanation of N-aryltetrahydroisoquinoline induced by visible light for the synthesis of α-aminonitrile using potassium thiocyanate as a “CN” agent
title_full Oxidative cyanation of N-aryltetrahydroisoquinoline induced by visible light for the synthesis of α-aminonitrile using potassium thiocyanate as a “CN” agent
title_fullStr Oxidative cyanation of N-aryltetrahydroisoquinoline induced by visible light for the synthesis of α-aminonitrile using potassium thiocyanate as a “CN” agent
title_full_unstemmed Oxidative cyanation of N-aryltetrahydroisoquinoline induced by visible light for the synthesis of α-aminonitrile using potassium thiocyanate as a “CN” agent
title_short Oxidative cyanation of N-aryltetrahydroisoquinoline induced by visible light for the synthesis of α-aminonitrile using potassium thiocyanate as a “CN” agent
title_sort oxidative cyanation of n-aryltetrahydroisoquinoline induced by visible light for the synthesis of α-aminonitrile using potassium thiocyanate as a “cn” agent
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071963/
https://www.ncbi.nlm.nih.gov/pubmed/35531501
http://dx.doi.org/10.1039/c9ra06120g
work_keys_str_mv AT yibing oxidativecyanationofnaryltetrahydroisoquinolineinducedbyvisiblelightforthesynthesisofaaminonitrileusingpotassiumthiocyanateasacnagent
AT yanning oxidativecyanationofnaryltetrahydroisoquinolineinducedbyvisiblelightforthesynthesisofaaminonitrileusingpotassiumthiocyanateasacnagent
AT yiniannian oxidativecyanationofnaryltetrahydroisoquinolineinducedbyvisiblelightforthesynthesisofaaminonitrileusingpotassiumthiocyanateasacnagent
AT xieyanjun oxidativecyanationofnaryltetrahydroisoquinolineinducedbyvisiblelightforthesynthesisofaaminonitrileusingpotassiumthiocyanateasacnagent
AT wenxiaoyong oxidativecyanationofnaryltetrahydroisoquinolineinducedbyvisiblelightforthesynthesisofaaminonitrileusingpotassiumthiocyanateasacnagent
AT auchaktong oxidativecyanationofnaryltetrahydroisoquinolineinducedbyvisiblelightforthesynthesisofaaminonitrileusingpotassiumthiocyanateasacnagent
AT landonghui oxidativecyanationofnaryltetrahydroisoquinolineinducedbyvisiblelightforthesynthesisofaaminonitrileusingpotassiumthiocyanateasacnagent

Ejemplares similares