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Discovery of diazahexa/hepta cyclic cage-like compounds with broad-spectrum antifungal activity against Candida and Cryptococcus species

Invasive fungal infections caused by Candida and Cryptococcus species lead to life threating infections in immunocompromised individuals. Furthermore, increasing incidence of fungal strains resistant to FDA-approved antifungal drugs along with the paucity of antifungal drugs warrants novel drugs to...

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Detalles Bibliográficos
Autores principales: Weinstock, Anthony, Arumugam, Natarajan, Almansour, Abdulrahman I., Kumar, Raju Suresh, Thangamani, Shankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071976/
https://www.ncbi.nlm.nih.gov/pubmed/35531520
http://dx.doi.org/10.1039/c9ra05777c