Novel camphor-based pyrimidine derivatives induced cancer cell death through a ROS-mediated mitochondrial apoptosis pathway

A series of novel camphor-based pyrimidine derivatives (3a–3x) have been synthesized; their structures were determined by using conventional methods and compound 3f was further confirmed through single crystal XRD analysis. The cytotoxic activity of the target compounds against a panel of human norm...

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Detalles Bibliográficos
Autores principales: Zhang, Yan, Wang, Yunyun, Zhao, Yuxun, Gu, Wen, Zhu, Yongqiang, Wang, Shifa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071996/
https://www.ncbi.nlm.nih.gov/pubmed/35531556
http://dx.doi.org/10.1039/c9ra05900h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071996/
https://www.ncbi.nlm.nih.gov/pubmed/35531556
http://dx.doi.org/10.1039/c9ra05900h

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