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嵌合抗原受体T细胞靶向LMP1抗原治疗EB病毒阳性淋巴瘤的功能研究

OBJECTIVE: This study aimed to create a type of CAR-T cells that targets LMP1 antigen and study its immunotherapeutic effect on LMP1-positive hematological malignancies. METHODS: To generate LMP1 CAR-T cells, a plasmid expressing LMP1 CAR was created using molecular cloning technology, and T cells w...

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Detalles Bibliográficos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial office of Chinese Journal of Hematology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072074/
https://www.ncbi.nlm.nih.gov/pubmed/35405781
http://dx.doi.org/10.3760/cma.j.issn.0253-2727.2022.03.008

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