Cargando…
A novel ratiometric fluorescent probe for the selective determination of HClO based on the ESIPT mechanism and its application in real samples
Based on the ESIPT fluorescence mechanism, herein, a novel ratiometric fluorescent probe was designed and synthesized for the detection of HClO. The reaction site of diaminomaleonitrile at the ortho-position of the phenolic hydroxyl group made the probe exhibit a ratiometric fluorescence response to...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072169/ https://www.ncbi.nlm.nih.gov/pubmed/35529410 http://dx.doi.org/10.1039/c9ra04569d |
_version_ | 1784700999437385728 |
---|---|
author | Li, Jingrui Gong, Aijun Shi, Guoqing Chai, Chengwen |
author_facet | Li, Jingrui Gong, Aijun Shi, Guoqing Chai, Chengwen |
author_sort | Li, Jingrui |
collection | PubMed |
description | Based on the ESIPT fluorescence mechanism, herein, a novel ratiometric fluorescent probe was designed and synthesized for the detection of HClO. The reaction site of diaminomaleonitrile at the ortho-position of the phenolic hydroxyl group made the probe exhibit a ratiometric fluorescence response towards hypochlorous acid (HClO). The specific sensing mechanism was verified via MS, HPLC and (1)H NMR spectroscopy. Moreover, the probe showed excellent performance with high sensitivity and good selectivity towards HClO in the presence of other reactive oxygen species. In addition, the probe was successfully applied to detect HClO spiked in tap water, river water and diluted human serum with good recoveries. |
format | Online Article Text |
id | pubmed-9072169 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | The Royal Society of Chemistry |
record_format | MEDLINE/PubMed |
spelling | pubmed-90721692022-05-06 A novel ratiometric fluorescent probe for the selective determination of HClO based on the ESIPT mechanism and its application in real samples Li, Jingrui Gong, Aijun Shi, Guoqing Chai, Chengwen RSC Adv Chemistry Based on the ESIPT fluorescence mechanism, herein, a novel ratiometric fluorescent probe was designed and synthesized for the detection of HClO. The reaction site of diaminomaleonitrile at the ortho-position of the phenolic hydroxyl group made the probe exhibit a ratiometric fluorescence response towards hypochlorous acid (HClO). The specific sensing mechanism was verified via MS, HPLC and (1)H NMR spectroscopy. Moreover, the probe showed excellent performance with high sensitivity and good selectivity towards HClO in the presence of other reactive oxygen species. In addition, the probe was successfully applied to detect HClO spiked in tap water, river water and diluted human serum with good recoveries. The Royal Society of Chemistry 2019-09-30 /pmc/articles/PMC9072169/ /pubmed/35529410 http://dx.doi.org/10.1039/c9ra04569d Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/ |
spellingShingle | Chemistry Li, Jingrui Gong, Aijun Shi, Guoqing Chai, Chengwen A novel ratiometric fluorescent probe for the selective determination of HClO based on the ESIPT mechanism and its application in real samples |
title | A novel ratiometric fluorescent probe for the selective determination of HClO based on the ESIPT mechanism and its application in real samples |
title_full | A novel ratiometric fluorescent probe for the selective determination of HClO based on the ESIPT mechanism and its application in real samples |
title_fullStr | A novel ratiometric fluorescent probe for the selective determination of HClO based on the ESIPT mechanism and its application in real samples |
title_full_unstemmed | A novel ratiometric fluorescent probe for the selective determination of HClO based on the ESIPT mechanism and its application in real samples |
title_short | A novel ratiometric fluorescent probe for the selective determination of HClO based on the ESIPT mechanism and its application in real samples |
title_sort | novel ratiometric fluorescent probe for the selective determination of hclo based on the esipt mechanism and its application in real samples |
topic | Chemistry |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072169/ https://www.ncbi.nlm.nih.gov/pubmed/35529410 http://dx.doi.org/10.1039/c9ra04569d |
work_keys_str_mv | AT lijingrui anovelratiometricfluorescentprobefortheselectivedeterminationofhclobasedontheesiptmechanismanditsapplicationinrealsamples AT gongaijun anovelratiometricfluorescentprobefortheselectivedeterminationofhclobasedontheesiptmechanismanditsapplicationinrealsamples AT shiguoqing anovelratiometricfluorescentprobefortheselectivedeterminationofhclobasedontheesiptmechanismanditsapplicationinrealsamples AT chaichengwen anovelratiometricfluorescentprobefortheselectivedeterminationofhclobasedontheesiptmechanismanditsapplicationinrealsamples AT lijingrui novelratiometricfluorescentprobefortheselectivedeterminationofhclobasedontheesiptmechanismanditsapplicationinrealsamples AT gongaijun novelratiometricfluorescentprobefortheselectivedeterminationofhclobasedontheesiptmechanismanditsapplicationinrealsamples AT shiguoqing novelratiometricfluorescentprobefortheselectivedeterminationofhclobasedontheesiptmechanismanditsapplicationinrealsamples AT chaichengwen novelratiometricfluorescentprobefortheselectivedeterminationofhclobasedontheesiptmechanismanditsapplicationinrealsamples |