The FAPα-activated prodrug Z-GP-DAVLBH inhibits the growth and pulmonary metastasis of osteosarcoma cells by suppressing the AXL pathway

Osteosarcoma is a kind of bone tumor with highly proliferative and invasive properties, a high incidence of pulmonary metastasis and a poor prognosis. Chemotherapy is the mainstay of treatment for osteosarcoma. Currently, there are no molecular targeted drugs approved for osteosarcoma treatment, par...

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Detalles Bibliográficos
Autores principales: Ye, Geni, Huang, Maohua, Li, Yong, Ouyang, Jie, Chen, Minfeng, Wen, Qing, Li, Xiaobo, Zeng, Huhu, Long, Pei, Fan, Zepei, Yin, Junqiang, Ye, Wencai, Zhang, Dongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072247/
https://www.ncbi.nlm.nih.gov/pubmed/35530139
http://dx.doi.org/10.1016/j.apsb.2021.08.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072247/
https://www.ncbi.nlm.nih.gov/pubmed/35530139
http://dx.doi.org/10.1016/j.apsb.2021.08.015

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