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Co-delivery of photosensitizer and diclofenac through sequentially responsive bilirubin nanocarriers for combating hypoxic tumors
Considering that photodynamic therapy (PDT)-induced oxygen consumption and microvascular damage could exacerbate hypoxia to drive more glycolysis and angiogenesis, a novel approach to potentiate PDT and overcome the resistances of hypoxia is avidly needed. Herein, morpholine-modified PEGylated bilir...
Autores principales: | Zhou, Yang, Tong, Fan, Gu, Weilong, He, Siqin, Yang, Xiaotong, Li, Jiamei, Gao, Yue-Dong, Gao, Huile |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072251/ https://www.ncbi.nlm.nih.gov/pubmed/35530138 http://dx.doi.org/10.1016/j.apsb.2021.12.001 |
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