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Concise synthesis of N-thiomethyl benzoimidazoles through base-promoted sequential multicomponent assembly

An efficient method for the synthesis of N-thiomethyl benzimidazoles from o-phenylenediamines, thiophenols, and aldehydes via C–N/C–S bond formation under metal-free conditions is described. A broad range of functional groups attached to the substrates were well tolerated in this reaction system. St...

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Detalles Bibliográficos
Autores principales: Tian, Jingxin, Yuan, Shanshan, Xiao, Fuhong, Huang, Huawen, Deng, Guo-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072308/
https://www.ncbi.nlm.nih.gov/pubmed/35530231
http://dx.doi.org/10.1039/c9ra06144d

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