Cargando…

K(ATP) channel dependent heart multiome atlas

Plasmalemmal ATP sensitive potassium (K(ATP)) channels are recognized metabolic sensors, yet their cellular reach is less well understood. Here, transgenic Kir6.2 null hearts devoid of the K(ATP) channel pore underwent multiomics surveillance and systems interrogation versus wildtype counterparts. D...

Descripción completa

Detalles Bibliográficos
Autores principales:	Arrell, D. Kent, Park, Sungjo, Yamada, Satsuki, Alekseev, Alexey E., Garmany, Armin, Jeon, Ryounghoon, Vuckovic, Ivan, Lindor, Jelena Zlatkovic, Terzic, Andre
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072320/ https://www.ncbi.nlm.nih.gov/pubmed/35513538 http://dx.doi.org/10.1038/s41598-022-11323-4

Ejemplares similares

Screening for regenerative therapy responders in heart failure
por: Yamada, Satsuki, et al.
Publicado: (2021)

Secretome signature of cardiopoietic cells echoed in rescued infarcted heart proteome
por: Arrell, D. Kent, et al.
Publicado: (2021)

Longevity leap: mind the healthspan gap
por: Garmany, Armin, et al.
Publicado: (2021)

Mechanical Dyssynchrony Precedes QRS Widening in ATP‐Sensitive K(+) Channel–Deficient Dilated Cardiomyopathy
por: Yamada, Satsuki, et al.
Publicado: (2013)

Role for SUR2A ED Domain in Allosteric Coupling within the K(ATP) Channel Complex
por: Karger, Amy B., et al.
Publicado: (2008)

Role of α2-Adrenoceptor Subtypes in Suppression of L-Type Ca(2+) Current in Mouse Cardiac Myocytes
por: Evdokimovskii, Edward V., et al.
Publicado: (2021)

Regenerative Therapy Prevents Heart Failure Progression in Dyssynchronous Nonischemic Narrow QRS Cardiomyopathy
por: Yamada, Satsuki, et al.
Publicado: (2015)

Ligand-insensitive State of Cardiac ATP-sensitive K(+) Channels : Basis for Channel Opening
por: Alekseev, Alexey E., et al.
Publicado: (1998)

Conventional and unconventional secretory proteins expressed with silkworm bombyxin signal peptide display functional fidelity
por: Park, Sungjo, et al.
Publicado: (2017)

Cardiopoietic stem cell therapy restores infarction-altered cardiac proteome
por: Arrell, D. Kent, et al.
Publicado: (2020)

Cardiopoietic programming of embryonic stem cells for tumor-free heart repair
por: Behfar, Atta, et al.
Publicado: (2007)

Ventricular remodeling in ischemic heart failure stratifies responders to stem cell therapy
por: Yamada, Satsuki, et al.
Publicado: (2019)

Subpopulations of miniature pig mesenchymal stromal cells with different differentiation potentials differ in the expression of octamer-binding transcription factor 4 and sex determining region Y-box 2
por: Jeon, Ryounghoon, et al.
Publicado: (2020)

Brachyury engineers cardiac repair competent stem cells
por: Li, Mark, et al.
Publicado: (2020)

Stem cell systems informatics for advanced clinical biodiagnostics: tracing molecular signatures from bench to bedside
por: Faustino, Randolph S., et al.
Publicado: (2013)

Reparative resynchronization in ischemic heart failure: an emerging strategy
por: Yamada, Satsuki, et al.
Publicado: (2014)

Path Toward Proactive Therapy for Patent Ductus Arteriosus
por: Yamada, Satsuki, et al.
Publicado: (2019)

Interferon Gamma Induces Reversible Metabolic Reprogramming of M1 Macrophages to Sustain Cell Viability and Pro-Inflammatory Activity
por: Wang, Feilong, et al.
Publicado: (2018)

The Essentials of Multiomics
por: Marshall, John L, et al.
Publicado: (2022)

Mass Customized Outlook for Regenerative Heart Failure Care
por: Yamada, Satsuki, et al.
Publicado: (2021)

ATP Release Channels
por: Taruno, Akiyuki
Publicado: (2018)

How ATP Inhibits the Open K(ATP) Channel
por: Craig, Tim J., et al.
Publicado: (2008)

Human K(ATP) channelopathies: diseases of metabolic homeostasis
por: Olson, Timothy M., et al.
Publicado: (2009)

Molecular Analysis of ATP-sensitive K Channel Gating and Implications for Channel Inhibition by ATP
por: Trapp, Stefan, et al.
Publicado: (1998)

Human acetyl-CoA carboxylase 2 expressed in silkworm Bombyx mori exhibits posttranslational biotinylation and phosphorylation
por: Hwang, In-Wook, et al.
Publicado: (2014)

Multiomic atlas with functional stratification and developmental dynamics of zebrafish cis-regulatory elements
por: Baranasic, Damir, et al.
Publicado: (2022)

Induced pluripotent stem cells: advances to applications
por: Nelson, Timothy J, et al.
Publicado: (2009)

SDF-1α/OPF/BP Composites Enhance the Migrating and Osteogenic Abilities of Mesenchymal Stem Cells
por: Li, Linli, et al.
Publicado: (2021)

ATP-sensitive potassium channel (K(ATP )channel) expression in the normal canine pancreas and in canine insulinomas
por: Donley, Vicky R, et al.
Publicado: (2005)

The dynamic interplay of PIP(2) and ATP in the regulation of the K(ATP) channel
por: Pipatpolkai, Tanadet, et al.
Publicado: (2022)

ATP release via anion channels
por: Sabirov, Ravshan Z., et al.
Publicado: (2005)

The mechanism of KATP channel inhibition by ATP
Publicado: (1991)

Embracing Integrative Multiomics Approaches
por: Rotroff, Daniel M., et al.
Publicado: (2016)

Multiomic immune clockworks of pregnancy
por: Peterson, Laura S., et al.
Publicado: (2020)

Multiomics Profiling Reveals Signatures of Dysmetabolism in Urban Populations in Central India
por: Monaghan, Tanya M., et al.
Publicado: (2021)

Evidence for a K(ATP) Channel in Rough Endoplasmic Reticulum (rerK(ATP) Channel) of Rat Hepatocytes
por: Salari, Sajjad, et al.
Publicado: (2015)

ATP and Sulfonylurea Linkage in the K(ATP) Channel Solves a Diabetes Puzzler
por: Drain, Peter
Publicado: (2013)

Easy Oracle SQL: get started fast writing SQL reports with SQL*Plus
por: Garmany, John
Publicado: (2005)

Mice expressing a human K(ATP) channel mutation have altered channel ATP sensitivity but no cardiac abnormalities
por: Clark, R., et al.
Publicado: (2012)

Open State Destabilization by Atp Occupancy Is Mechanism Speeding Burst Exit Underlying K(ATP) Channel Inhibition by Atp
por: Li, Lehong, et al.
Publicado: (2002)

Cannot write session to /tmp/vufind_sessions/sess_7j1oikkksm50rpnogdc5t4ifi5