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Synergistic Pd/Cu-catalyzed enantioselective Csp(2)–F bond alkylation of fluoro-1,3-dienes with aldimine esters
Due to high bond dissociation energies of Csp(2)–F bonds, using fluorinated compounds in Csp(2)–Csp(3) cross-coupling is difficult. Here the authors report a protocol for enantioselective Csp(2)–Csp(3) coupling of dienyl fluorides with aldimine esters, enabled by synergistic copper and palladium cat...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072389/ https://www.ncbi.nlm.nih.gov/pubmed/35513394 http://dx.doi.org/10.1038/s41467-022-30152-7 |