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Ketone body and FGF21 coordinately regulate fasting-induced oxidative stress response in the heart

Ketone body β-hydroxybutyrate (βOHB) and fibroblast growth factor-21 (FGF21) have been proposed to mediate systemic metabolic response to fasting. However, it remains elusive about the signaling elicited by ketone and FGF21 in the heart. Stimulation of neonatal rat cardiomyocytes with βOHB and FGF21...

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Detalles Bibliográficos
Autores principales: Kawakami, Ryo, Sunaga, Hiroaki, Iso, Tatsuya, Kaneko, Ryosuke, Koitabashi, Norimichi, Obokata, Masaru, Harada, Tomonari, Matsui, Hiroki, Yokoyama, Tomoyuki, Kurabayashi, Masahiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072431/
https://www.ncbi.nlm.nih.gov/pubmed/35513524
http://dx.doi.org/10.1038/s41598-022-10993-4