Cargando…

Ketone body and FGF21 coordinately regulate fasting-induced oxidative stress response in the heart

Ketone body β-hydroxybutyrate (βOHB) and fibroblast growth factor-21 (FGF21) have been proposed to mediate systemic metabolic response to fasting. However, it remains elusive about the signaling elicited by ketone and FGF21 in the heart. Stimulation of neonatal rat cardiomyocytes with βOHB and FGF21...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kawakami, Ryo, Sunaga, Hiroaki, Iso, Tatsuya, Kaneko, Ryosuke, Koitabashi, Norimichi, Obokata, Masaru, Harada, Tomonari, Matsui, Hiroki, Yokoyama, Tomoyuki, Kurabayashi, Masahiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072431/ https://www.ncbi.nlm.nih.gov/pubmed/35513524 http://dx.doi.org/10.1038/s41598-022-10993-4

Ejemplares similares

Activation of cardiac AMPK-FGF21 feed-forward loop in acute myocardial infarction: Role of adrenergic overdrive and lipolysis byproducts
por: Sunaga, Hiroaki, et al.
Publicado: (2019)

Prognostic impact of elevated fatty acid‐binding protein 1 in patients with heart failure
por: Kagami, Kazuki, et al.
Publicado: (2021)

Pathophysiological role of fatty acid‐binding protein 4 in Asian patients with heart failure and preserved ejection fraction
por: Harada, Tomonari, et al.
Publicado: (2020)

DPP-4 inhibitor induces FGF21 expression via sirtuin 1 signaling and improves myocardial energy metabolism
por: Furukawa, Nozomi, et al.
Publicado: (2020)

Association Between Circulating Ketone Bodies and Worse Outcomes in Hemodialysis Patients
por: Obokata, Masaru, et al.
Publicado: (2017)

Fatty Acid Binding Protein 4 and 5 Play a Crucial Role in Thermogenesis under the Conditions of Fasting and Cold Stress
por: Syamsunarno, Mas Rizky A. A., et al.
Publicado: (2014)

Urinary FABP1 is a biomarker for impaired proximal tubular protein reabsorption and is synergistically enhanced by concurrent liver injury
por: Kawakami, Ryo, et al.
Publicado: (2021)

Pathophysiological and diagnostic importance of fatty acid-binding protein 1 in heart failure with preserved ejection fraction
por: Harada, Tomonari, et al.
Publicado: (2021)

Elongation of Long‐Chain Fatty Acid Family Member 6 (Elovl6)‐Driven Fatty Acid Metabolism Regulates Vascular Smooth Muscle Cell Phenotype Through AMP‐Activated Protein Kinase/Krüppel‐Like Factor 4 (AMPK/KLF4) Signaling
por: Sunaga, Hiroaki, et al.
Publicado: (2016)

Pressure mediated hypertrophy and mechanical stretch up-regulate expression of the long form of leptin receptor (ob-Rb) in rat cardiac myocytes
por: Matsui, Hiroki, et al.
Publicado: (2012)

Unilateral Lung Congestion During Exercise in a Patient With a Single Pulmonary Vein Stenosis
por: Kato, Toshimitsu, et al.
Publicado: (2021)

Reduced fatty acid uptake aggravates cardiac contractile dysfunction in streptozotocin-induced diabetic cardiomyopathy
por: Umbarawan, Yogi, et al.
Publicado: (2020)

Reduced Fatty Acid Use from CD36 Deficiency Deteriorates Streptozotocin-Induced Diabetic Cardiomyopathy in Mice
por: Umbarawan, Yogi, et al.
Publicado: (2021)

Pathophysiologic Contributions of Visceral Adiposity to Left Ventricular Diastolic Dysfunction
por: Nagata, Reika, et al.
Publicado: (2023)

Empagliflozin induces the transcriptional program for nutrient homeostasis in skeletal muscle in normal mice
por: Kawakami, Ryo, et al.
Publicado: (2023)

Periostin-expressing cell-specific transforming growth factor-β inhibition in pulmonary artery prevents pulmonary arterial hypertension
por: Seki, Mitsuru, et al.
Publicado: (2019)

Impact of uric acid on incident hypertension: Sex-specific analysis in different age groups
por: Ohyama, Yoshiaki, et al.
Publicado: (2019)

Nonbacterial Thrombotic Endocarditis—A Rare Case of Acute Libman-Sacks Endocarditis Complicated by Multiple Cerebral Infarcts: Case Report and Literature Review
por: Kato, Toshimitsu, et al.
Publicado: (2020)

Stearoyl-CoA Desaturase-1 (SCD1) Augments Saturated Fatty Acid-Induced Lipid Accumulation and Inhibits Apoptosis in Cardiac Myocytes
por: Matsui, Hiroki, et al.
Publicado: (2012)

Exercise endurance capacity is markedly reduced due to impaired energy homeostasis during prolonged fasting in FABP4/5 deficient mice
por: Iso, Tatsuya, et al.
Publicado: (2019)

Myocardial fatty acid uptake through CD36 is indispensable for sufficient bioenergetic metabolism to prevent progression of pressure overload-induced heart failure
por: Umbarawan, Yogi, et al.
Publicado: (2018)

Glucose is preferentially utilized for biomass synthesis in pressure-overloaded hearts: evidence from fatty acid-binding protein-4 and -5 knockout mice
por: Umbarawan, Yogi, et al.
Publicado: (2018)

CD36 is indispensable for nutrient homeostasis and endurance exercise capacity during prolonged fasting
por: Iso, Tatsuya, et al.
Publicado: (2018)

A Critical Role of Fatty Acid Binding Protein 4 and 5 (FABP4/5) in the Systemic Response to Fasting
por: Syamsunarno, Mas Rizky A. A., et al.
Publicado: (2013)

Remarkable regression of massive deep vein thrombosis in response to intensive oral rivaroxaban treatment
por: Koitabashi, Norimichi, et al.
Publicado: (2015)

Adaptive Servo-ventilation Therapy Results in the Prevention of Arrhythmias in Patients with Heart Failure Due to Ischemic Heart Disease
por: Nagasaka, Takashi, et al.
Publicado: (2021)

Cardiac Metabolism and Contractile Function in Mice with Reduced Trans-Endothelial Fatty Acid Transport
por: Iso, Tatsuya, et al.
Publicado: (2021)

Acute myocarditis associated with COVID-19 vaccination: A case report
por: Nagasaka, Takashi, et al.
Publicado: (2021)

Effect of Inferior Vena Cava Filter on Venous Thromboembolism Mortality in Japan　― JROAD and JROAD-DPC Registry Analysis ―
por: Ohyama, Yoshiaki, et al.
Publicado: (2019)

Exercise Stress Echocardiography in the Diagnostic Evaluation of Heart Failure with Preserved Ejection Fraction
por: Harada, Tomonari, et al.
Publicado: (2022)

A Risk Score with Additional Four Independent Factors to Predict the Incidence and Recovery from Metabolic Syndrome: Development and Validation in Large Japanese Cohorts
por: Obokata, Masaru, et al.
Publicado: (2015)

Circulating FABP4 is eliminated by the kidney via glomerular filtration followed by megalin-mediated reabsorption
por: Shrestha, Suman, et al.
Publicado: (2018)

The H(2)FPEF and HFA-PEFF algorithms for predicting exercise intolerance and abnormal hemodynamics in heart failure with preserved ejection fraction
por: Amanai, Shiro, et al.
Publicado: (2022)

Diastolic Filling Time, Chronotropic Response, and Exercise Capacity in Heart Failure and Preserved Ejection Fraction With Sinus Rhythm
por: Kagami, Kazuki, et al.
Publicado: (2022)

Comparative effects of long-acting and short-acting loop diuretics on cardiac sympathetic nerve activity in patients with chronic heart failure
por: Matsuo, Yae, et al.
Publicado: (2016)

Effects of Statin Therapy on Cardiac Sympathetic Nerve Activity and Left Ventricular Remodeling in Patients With Chronic Heart Failure: A Propensity Score-Matched Analysis
por: Sano, Hirokazu, et al.
Publicado: (2014)

A case of a middle-aged patient with a ventricular septal defect complicated by severe pulmonary hypertension-stepwise surgical repair with pulmonary vasodilators-
por: Kanai, Anna, et al.
Publicado: (2021)

Sex differences in left ventricular afterload and diastolic function are independent from the aortic size
por: Sorimachi, Hidemi, et al.
Publicado: (2019)

Adiposity and clinical outcomes in East Asian patients with heart failure and preserved ejection fraction
por: Seki, Yuko, et al.
Publicado: (2022)

Visual echocardiographic scoring system of the left ventricular filling pressure and outcomes of heart failure with preserved ejection fraction
por: Murayama, Michito, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_v9m2m7arbbdam0sn2lmlmuip0k