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Functional role of the Frizzled linker domain in the Wnt signaling pathway

The Wnt signaling pathway plays a critical role in the developmental and physiological processes of metazoans. We previously reported that the Frizzled4 (FZD4) linker domain plays an important role in Norrin binding and signaling. However, the question remains whether the FZD linker contributes to W...

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Detalles Bibliográficos
Autores principales: Ko, Seung-Bum, Mihara, Emiko, Park, Yedarm, Roh, Kyeonghwan, Kang, Chanhee, Takagi, Junichi, Bang, Injin, Choi, Hee-Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072438/
https://www.ncbi.nlm.nih.gov/pubmed/35513706
http://dx.doi.org/10.1038/s42003-022-03370-4