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Quantifiable urine glyphosate levels detected in 99% of the French population, with higher values in men, in younger people, and in farmers

France is the first pesticide-consuming country in Europe. Glyphosate is the most used pesticide worldwide and glyphosate is detected in the general population of industrialized countries, with higher levels found in farmers and children. Little data was available concerning exposure in France. Our...

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Autores principales: Grau, Daniel, Grau, Nicole, Gascuel, Quentin, Paroissin, Christian, Stratonovitch, Cécile, Lairon, Denis, Devault, Damien A., Di Cristofaro, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072501/
https://www.ncbi.nlm.nih.gov/pubmed/35018595
http://dx.doi.org/10.1007/s11356-021-18110-0
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author Grau, Daniel
Grau, Nicole
Gascuel, Quentin
Paroissin, Christian
Stratonovitch, Cécile
Lairon, Denis
Devault, Damien A.
Di Cristofaro, Julie
author_facet Grau, Daniel
Grau, Nicole
Gascuel, Quentin
Paroissin, Christian
Stratonovitch, Cécile
Lairon, Denis
Devault, Damien A.
Di Cristofaro, Julie
author_sort Grau, Daniel
collection PubMed
description France is the first pesticide-consuming country in Europe. Glyphosate is the most used pesticide worldwide and glyphosate is detected in the general population of industrialized countries, with higher levels found in farmers and children. Little data was available concerning exposure in France. Our objective was to determine glyphosate levels in the French general population and to search for an association with seasons, biological features, lifestyle status, dietary habits, and occupational exposure. This study includes 6848 participants recruited between 2018 and 2020. Associated data include age, gender, location, employment status, and dietary information. Glyphosate was quantified by a single laboratory in first-void urine samples using ELISA. Our results support a general contamination of the French population, with glyphosate quantifiable in 99.8% of urine samples with a mean of 1.19 ng/ml + / − 0.84 after adjustment to body mass index (BMI). We confirm higher glyphosate levels in men and children. Our results support glyphosate contamination through food and water intake, as lower glyphosate levels are associated with dominant organic food intake and filtered water. Higher occupational exposure is confirmed in farmers and farmers working in wine-growing environment. Thus, our present results show a general contamination of the French population with glyphosate, and further contribute to the description of a widespread contamination in industrialized countries.
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spelling pubmed-90725012022-05-07 Quantifiable urine glyphosate levels detected in 99% of the French population, with higher values in men, in younger people, and in farmers Grau, Daniel Grau, Nicole Gascuel, Quentin Paroissin, Christian Stratonovitch, Cécile Lairon, Denis Devault, Damien A. Di Cristofaro, Julie Environ Sci Pollut Res Int Research Article France is the first pesticide-consuming country in Europe. Glyphosate is the most used pesticide worldwide and glyphosate is detected in the general population of industrialized countries, with higher levels found in farmers and children. Little data was available concerning exposure in France. Our objective was to determine glyphosate levels in the French general population and to search for an association with seasons, biological features, lifestyle status, dietary habits, and occupational exposure. This study includes 6848 participants recruited between 2018 and 2020. Associated data include age, gender, location, employment status, and dietary information. Glyphosate was quantified by a single laboratory in first-void urine samples using ELISA. Our results support a general contamination of the French population, with glyphosate quantifiable in 99.8% of urine samples with a mean of 1.19 ng/ml + / − 0.84 after adjustment to body mass index (BMI). We confirm higher glyphosate levels in men and children. Our results support glyphosate contamination through food and water intake, as lower glyphosate levels are associated with dominant organic food intake and filtered water. Higher occupational exposure is confirmed in farmers and farmers working in wine-growing environment. Thus, our present results show a general contamination of the French population with glyphosate, and further contribute to the description of a widespread contamination in industrialized countries. Springer Berlin Heidelberg 2022-01-12 2022 /pmc/articles/PMC9072501/ /pubmed/35018595 http://dx.doi.org/10.1007/s11356-021-18110-0 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Research Article
Grau, Daniel
Grau, Nicole
Gascuel, Quentin
Paroissin, Christian
Stratonovitch, Cécile
Lairon, Denis
Devault, Damien A.
Di Cristofaro, Julie
Quantifiable urine glyphosate levels detected in 99% of the French population, with higher values in men, in younger people, and in farmers
title Quantifiable urine glyphosate levels detected in 99% of the French population, with higher values in men, in younger people, and in farmers
title_full Quantifiable urine glyphosate levels detected in 99% of the French population, with higher values in men, in younger people, and in farmers
title_fullStr Quantifiable urine glyphosate levels detected in 99% of the French population, with higher values in men, in younger people, and in farmers
title_full_unstemmed Quantifiable urine glyphosate levels detected in 99% of the French population, with higher values in men, in younger people, and in farmers
title_short Quantifiable urine glyphosate levels detected in 99% of the French population, with higher values in men, in younger people, and in farmers
title_sort quantifiable urine glyphosate levels detected in 99% of the french population, with higher values in men, in younger people, and in farmers
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072501/
https://www.ncbi.nlm.nih.gov/pubmed/35018595
http://dx.doi.org/10.1007/s11356-021-18110-0
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