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Diffusion control in biochemical specificity

Biochemical specificity is critical in enzyme function, evolution, and engineering. Here we employ an established kinetic model to dissect the effects of reactant geometry and diffusion on product formation speed and accuracy in the presence of cognate (correct) and near-cognate (incorrect) substrat...

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Detalles Bibliográficos
Autores principales: Alejo, Jose L., Kempes, Christopher P., Adamala, Katarzyna P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072584/
https://www.ncbi.nlm.nih.gov/pubmed/35278424
http://dx.doi.org/10.1016/j.bpj.2022.03.005

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