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Acrylamide-dT: a polymerisable nucleoside for DNA incorporation

The synthesis of a novel modified nucleoside phosphoramidite, Acrylamide-dT-CE phosphoramidite, obtained in three steps from commercially available starting materials, is reported. It was readily incorporated into thrombin binding aptamer (TBA) sequences using automated solid-phase synthesis under u...

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Detalles Bibliográficos
Autores principales: Allabush, Francia, Mendes, Paula M., Tucker, James H. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072585/
https://www.ncbi.nlm.nih.gov/pubmed/35527933
http://dx.doi.org/10.1039/c9ra07570d

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