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The AMIGO1 adhesion protein activates Kv2.1 voltage sensors

Kv2 voltage-gated potassium channels are modulated by amphoterin-induced gene and open reading frame (AMIGO) neuronal adhesion proteins. Here, we identify steps in the conductance activation pathway of Kv2.1 channels that are modulated by AMIGO1 using voltage-clamp recordings and spectroscopy of het...

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Detalles Bibliográficos
Autores principales:	Sepela, Rebecka J., Stewart, Robert G., Valencia, Luis A., Thapa, Parashar, Wang, Zeming, Cohen, Bruce E., Sack, Jon T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Biophysical Society 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072587/ https://www.ncbi.nlm.nih.gov/pubmed/35314141 http://dx.doi.org/10.1016/j.bpj.2022.03.020

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