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Socioeconomic Factors Associated With Glycemic Measurement and Poor HbA1c Control in People With Type 2 Diabetes: The Global DISCOVER Study

DISCOVER is a 3-year observational study program of 15,983 people with type 2 diabetes initiating second-line glucose-lowering therapy in 38 countries. We investigated the association between socioeconomic status and both the availability of a baseline glycated hemoglobin (HbA1c) measurement and poo...

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Autores principales: Gomes, Marília B., Tang, Fengming, Chen, Hungta, Cid-Ruzafa, Javier, Fenici, Peter, Khunti, Kamlesh, Rathmann, Wolfgang, Shestakova, Marina V., Surmont, Filip, Watada, Hirotaka, Medina, Jesús, Shimomura, Iichiro, Saraiva, Gabriela Luporini, Cooper, Andrew, Nicolucci, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072655/
https://www.ncbi.nlm.nih.gov/pubmed/35527995
http://dx.doi.org/10.3389/fendo.2022.831676
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author Gomes, Marília B.
Tang, Fengming
Chen, Hungta
Cid-Ruzafa, Javier
Fenici, Peter
Khunti, Kamlesh
Rathmann, Wolfgang
Shestakova, Marina V.
Surmont, Filip
Watada, Hirotaka
Medina, Jesús
Shimomura, Iichiro
Saraiva, Gabriela Luporini
Cooper, Andrew
Nicolucci, Antonio
author_facet Gomes, Marília B.
Tang, Fengming
Chen, Hungta
Cid-Ruzafa, Javier
Fenici, Peter
Khunti, Kamlesh
Rathmann, Wolfgang
Shestakova, Marina V.
Surmont, Filip
Watada, Hirotaka
Medina, Jesús
Shimomura, Iichiro
Saraiva, Gabriela Luporini
Cooper, Andrew
Nicolucci, Antonio
author_sort Gomes, Marília B.
collection PubMed
description DISCOVER is a 3-year observational study program of 15,983 people with type 2 diabetes initiating second-line glucose-lowering therapy in 38 countries. We investigated the association between socioeconomic status and both the availability of a baseline glycated hemoglobin (HbA1c) measurement and poor glycemic control (HbA1c level ≥ 9.0%) in participants enrolled in DISCOVER. Factors associated with a lack of baseline HbA1c measurement or an HbA1c level ≥ 9.0% were assessed using three-level hierarchical logistic models. Overall, 19.1% of participants did not have a baseline HbA1c measurement recorded. Lower-middle country income (vs. high) and primary/no formal education (vs. university education) were independently associated with a reduced likelihood of having a baseline HbA1c measurement (odds ratio [95% confidence interval]: 0.11 [0.03–0.49] and 0.81 [0.66–0.98], respectively. Of the participants with an available HbA1c measurement, 26.9% had an HbA1c level ≥ 9.0%; 68.7% of these individuals were from lower- or upper-middle-income countries. Factors associated with an increased likelihood of poor glycemic control included low country income, treatment at a site with public and/or governmental funding (vs. private funding) and having public or no health insurance (vs. private). A substantial proportion of DISCOVER participants did not have an HbA1c measurement; more than one-quarter of these participants had poorly controlled type 2 diabetes. Both individual- and country-level socioeconomic factors are associated with the quality of care regarding glycemic control. Awareness of these factors could help improve the management of patients with type 2 diabetes.
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spelling pubmed-90726552022-05-07 Socioeconomic Factors Associated With Glycemic Measurement and Poor HbA1c Control in People With Type 2 Diabetes: The Global DISCOVER Study Gomes, Marília B. Tang, Fengming Chen, Hungta Cid-Ruzafa, Javier Fenici, Peter Khunti, Kamlesh Rathmann, Wolfgang Shestakova, Marina V. Surmont, Filip Watada, Hirotaka Medina, Jesús Shimomura, Iichiro Saraiva, Gabriela Luporini Cooper, Andrew Nicolucci, Antonio Front Endocrinol (Lausanne) Endocrinology DISCOVER is a 3-year observational study program of 15,983 people with type 2 diabetes initiating second-line glucose-lowering therapy in 38 countries. We investigated the association between socioeconomic status and both the availability of a baseline glycated hemoglobin (HbA1c) measurement and poor glycemic control (HbA1c level ≥ 9.0%) in participants enrolled in DISCOVER. Factors associated with a lack of baseline HbA1c measurement or an HbA1c level ≥ 9.0% were assessed using three-level hierarchical logistic models. Overall, 19.1% of participants did not have a baseline HbA1c measurement recorded. Lower-middle country income (vs. high) and primary/no formal education (vs. university education) were independently associated with a reduced likelihood of having a baseline HbA1c measurement (odds ratio [95% confidence interval]: 0.11 [0.03–0.49] and 0.81 [0.66–0.98], respectively. Of the participants with an available HbA1c measurement, 26.9% had an HbA1c level ≥ 9.0%; 68.7% of these individuals were from lower- or upper-middle-income countries. Factors associated with an increased likelihood of poor glycemic control included low country income, treatment at a site with public and/or governmental funding (vs. private funding) and having public or no health insurance (vs. private). A substantial proportion of DISCOVER participants did not have an HbA1c measurement; more than one-quarter of these participants had poorly controlled type 2 diabetes. Both individual- and country-level socioeconomic factors are associated with the quality of care regarding glycemic control. Awareness of these factors could help improve the management of patients with type 2 diabetes. Frontiers Media S.A. 2022-04-22 /pmc/articles/PMC9072655/ /pubmed/35527995 http://dx.doi.org/10.3389/fendo.2022.831676 Text en Copyright © 2022 Gomes, Tang, Chen, Cid-Ruzafa, Fenici, Khunti, Rathmann, Shestakova, Surmont, Watada, Medina, Shimomura, Saraiva, Cooper and Nicolucci https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Endocrinology
Gomes, Marília B.
Tang, Fengming
Chen, Hungta
Cid-Ruzafa, Javier
Fenici, Peter
Khunti, Kamlesh
Rathmann, Wolfgang
Shestakova, Marina V.
Surmont, Filip
Watada, Hirotaka
Medina, Jesús
Shimomura, Iichiro
Saraiva, Gabriela Luporini
Cooper, Andrew
Nicolucci, Antonio
Socioeconomic Factors Associated With Glycemic Measurement and Poor HbA1c Control in People With Type 2 Diabetes: The Global DISCOVER Study
title Socioeconomic Factors Associated With Glycemic Measurement and Poor HbA1c Control in People With Type 2 Diabetes: The Global DISCOVER Study
title_full Socioeconomic Factors Associated With Glycemic Measurement and Poor HbA1c Control in People With Type 2 Diabetes: The Global DISCOVER Study
title_fullStr Socioeconomic Factors Associated With Glycemic Measurement and Poor HbA1c Control in People With Type 2 Diabetes: The Global DISCOVER Study
title_full_unstemmed Socioeconomic Factors Associated With Glycemic Measurement and Poor HbA1c Control in People With Type 2 Diabetes: The Global DISCOVER Study
title_short Socioeconomic Factors Associated With Glycemic Measurement and Poor HbA1c Control in People With Type 2 Diabetes: The Global DISCOVER Study
title_sort socioeconomic factors associated with glycemic measurement and poor hba1c control in people with type 2 diabetes: the global discover study
topic Endocrinology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072655/
https://www.ncbi.nlm.nih.gov/pubmed/35527995
http://dx.doi.org/10.3389/fendo.2022.831676
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