Assessing positive and negative valence systems to refine animal models of bipolar disorders: the example of GBR 12909-induced manic phenotype

Bipolar disorders are defined by recurrences of depressive and manic episodes. The pathophysiology is still unknown, and translating clinical symptoms into behaviors explorable in animal models is challenging. Animal models of bipolar disorder do not exist because cyclicity of the disease is impossi...

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Detalles Bibliográficos
Autores principales: Bigot, Mathilde, Vicq, Eleonore, Lledo, Pierre-Marie, Alonso, Mariana, Henry, Chantal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072677/
https://www.ncbi.nlm.nih.gov/pubmed/35513683
http://dx.doi.org/10.1038/s41598-022-10965-8

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