TRIM47 is a novel endothelial activation factor that aggravates lipopolysaccharide-induced acute lung injury in mice via K63-linked ubiquitination of TRAF2

Endothelial activation plays an essential role in the pathogenesis of sepsis-induced acute lung injury, however, the detailed regulatory mechanisms remain largely unknown. Here, we reported that TRIM47, an E3 ubiquitin ligase of the tripartite motif-containing protein family, was highly expressed in...

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Detalles Bibliográficos
Autores principales: Qian, Yisong, Wang, Ziwei, Lin, Hongru, Lei, Tianhua, Zhou, Zhou, Huang, Weilu, Wu, Xuehan, Zuo, Li, Wu, Jie, Liu, Yu, Wang, Ling-Fang, Guan, Xiao-Hui, Deng, Ke-Yu, Fu, Mingui, Xin, Hong-Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072678/
https://www.ncbi.nlm.nih.gov/pubmed/35513381
http://dx.doi.org/10.1038/s41392-022-00953-9

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