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Patterns and mediators of racial and ethnic disparities in COVID-19 vaccine hesitancy among young adults
COVID-19 vaccines have been available for over a year, yet 26% of U.S. young adults remain unvaccinated. This study examines racial and ethnic disparities in young adult vaccine hesitancy and attitudes/beliefs that mediate disparities in vaccine hesitancy. Young adults (n = 2041;Mean[SD]:21.3[0.7] y...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072749/ https://www.ncbi.nlm.nih.gov/pubmed/35526673 http://dx.doi.org/10.1016/j.ypmed.2022.107077 |
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author | Dai, Hongying Barrington-Trimis, Jessica L. Unger, Jennifer B. Baezconde-Garbanati, Lourdes Leventhal, Adam M. |
author_facet | Dai, Hongying Barrington-Trimis, Jessica L. Unger, Jennifer B. Baezconde-Garbanati, Lourdes Leventhal, Adam M. |
author_sort | Dai, Hongying |
collection | PubMed |
description | COVID-19 vaccines have been available for over a year, yet 26% of U.S. young adults remain unvaccinated. This study examines racial and ethnic disparities in young adult vaccine hesitancy and attitudes/beliefs that mediate disparities in vaccine hesitancy. Young adults (n = 2041;Mean[SD]:21.3[0.7] years-old) from a Los Angeles, CA, USA cohort were surveyed online in January–May 2021 and classified as vaccine hesitant (those who reported “Not at all likely”/“Not very likely” /“Slightly likely” to get vaccinated) versus non-hesitant (those who reported “Moderately likely”/”Very likely”/”Definitely likely” to get vaccinated or already vaccinated). Multivariable logistic regression was performed to examine racial/ethnic disparities in vaccine hesitancy. Factor analysis was conducted to create three subscales toward vaccination: positive, negative, and lack-of-access beliefs. Mediation analyses were performed to assess pathways from attitude/belief subscales to racial disparities in vaccine hesitancy. Overall 33.0% of respondents reported vaccine hesitancy. Black vs. White young adults had a higher prevalence of vaccine hesitancy (AOR[95%CI] = 4.3[2.4–7.8]), and Asians vs. Whites had a lower prevalence (AOR[95%CI] = 0.5[0.3–0.8]). Mediators explained 90% of the Black (vs. White) disparity in vaccine hesitancy, including significant indirect effects through positive belief–reducing (β = 0.23,p < .001) and negative belief–enhancing (β = 0.02,p = .04) effects. About 81% of the Asian (vs. White) disparity in vaccine hesitancy was explained by the three combined subscales, including significant positive belief–reducing (β = −0.18,p < .001) indirect effect. Substantial racial and ethnic disparities in young adult COVID-19 vaccine hesitancy were found, which were mediated by differences in attitudes and beliefs toward vaccination. Targeted education campaigns and messages are needed to promote equitable utilization of the effective vaccine. |
format | Online Article Text |
id | pubmed-9072749 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Elsevier Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-90727492022-05-06 Patterns and mediators of racial and ethnic disparities in COVID-19 vaccine hesitancy among young adults Dai, Hongying Barrington-Trimis, Jessica L. Unger, Jennifer B. Baezconde-Garbanati, Lourdes Leventhal, Adam M. Prev Med Article COVID-19 vaccines have been available for over a year, yet 26% of U.S. young adults remain unvaccinated. This study examines racial and ethnic disparities in young adult vaccine hesitancy and attitudes/beliefs that mediate disparities in vaccine hesitancy. Young adults (n = 2041;Mean[SD]:21.3[0.7] years-old) from a Los Angeles, CA, USA cohort were surveyed online in January–May 2021 and classified as vaccine hesitant (those who reported “Not at all likely”/“Not very likely” /“Slightly likely” to get vaccinated) versus non-hesitant (those who reported “Moderately likely”/”Very likely”/”Definitely likely” to get vaccinated or already vaccinated). Multivariable logistic regression was performed to examine racial/ethnic disparities in vaccine hesitancy. Factor analysis was conducted to create three subscales toward vaccination: positive, negative, and lack-of-access beliefs. Mediation analyses were performed to assess pathways from attitude/belief subscales to racial disparities in vaccine hesitancy. Overall 33.0% of respondents reported vaccine hesitancy. Black vs. White young adults had a higher prevalence of vaccine hesitancy (AOR[95%CI] = 4.3[2.4–7.8]), and Asians vs. Whites had a lower prevalence (AOR[95%CI] = 0.5[0.3–0.8]). Mediators explained 90% of the Black (vs. White) disparity in vaccine hesitancy, including significant indirect effects through positive belief–reducing (β = 0.23,p < .001) and negative belief–enhancing (β = 0.02,p = .04) effects. About 81% of the Asian (vs. White) disparity in vaccine hesitancy was explained by the three combined subscales, including significant positive belief–reducing (β = −0.18,p < .001) indirect effect. Substantial racial and ethnic disparities in young adult COVID-19 vaccine hesitancy were found, which were mediated by differences in attitudes and beliefs toward vaccination. Targeted education campaigns and messages are needed to promote equitable utilization of the effective vaccine. Elsevier Inc. 2022-06 2022-05-06 /pmc/articles/PMC9072749/ /pubmed/35526673 http://dx.doi.org/10.1016/j.ypmed.2022.107077 Text en © 2022 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Dai, Hongying Barrington-Trimis, Jessica L. Unger, Jennifer B. Baezconde-Garbanati, Lourdes Leventhal, Adam M. Patterns and mediators of racial and ethnic disparities in COVID-19 vaccine hesitancy among young adults |
title | Patterns and mediators of racial and ethnic disparities in COVID-19 vaccine hesitancy among young adults |
title_full | Patterns and mediators of racial and ethnic disparities in COVID-19 vaccine hesitancy among young adults |
title_fullStr | Patterns and mediators of racial and ethnic disparities in COVID-19 vaccine hesitancy among young adults |
title_full_unstemmed | Patterns and mediators of racial and ethnic disparities in COVID-19 vaccine hesitancy among young adults |
title_short | Patterns and mediators of racial and ethnic disparities in COVID-19 vaccine hesitancy among young adults |
title_sort | patterns and mediators of racial and ethnic disparities in covid-19 vaccine hesitancy among young adults |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072749/ https://www.ncbi.nlm.nih.gov/pubmed/35526673 http://dx.doi.org/10.1016/j.ypmed.2022.107077 |
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