Intranasal Lentiviral Vector-Mediated Antibody Delivery Confers Reduction of SARS-CoV-2 Infection in Elderly and Immunocompromised Mice

Vaccines for COVID-19 are now a crucial public health need, but the degree of protection provided by conventional vaccinations for individuals with compromised immune systems is unclear. The use of viral vectors to express neutralizing monoclonal antibodies (mAbs) in the lung is an alternative appro...

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Detalles Bibliográficos
Autores principales: Du, Yue, Zhang, Shengnan, Zhang, Zhaoyong, Miah, Kamran M., Wei, Peilan, Zhang, Lu, Zhu, Yuhui, Li, Zhengtu, Ye, Feng, Gill, Deborah R., Hyde, Stephen C., Wang, Yanqun, Zhao, Jincun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072863/
https://www.ncbi.nlm.nih.gov/pubmed/35529866
http://dx.doi.org/10.3389/fimmu.2022.819058

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