Cargando…

Palladium-catalyzed oxidative cross-coupling for the synthesis of α-amino ketones

A novel oxidative cross-coupling reaction for the synthesis of α-aryl α-amino ketones in the presence of palladium catalysts using T(+)BF(4)(−) as an oxidant has been developed. This transformation was achieved by direct C–H oxidation of α-aminocarbonyl compounds and arylation. The mild reaction has...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wei, Xiao-Hong, Li, Zhen-Hua, Zhao, Lian-Biao, Zhang, Ping, Zhou, Han-Cheng, Wang, Yan-Bin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2019
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072988/ https://www.ncbi.nlm.nih.gov/pubmed/35530775 http://dx.doi.org/10.1039/c9ra06108h

Ejemplares similares

Enantioselective synthesis of α-amino ketones through palladium-catalyzed asymmetric arylation of α-keto imines
por: Wen, Wei, et al.
Publicado: (2022)

Electronically flexible PYA ligands for efficient palladium-catalyzed α-arylation of ketones
por: Reusser, Esaïe, et al.
Publicado: (2023)

A palladium-catalyzed C–H functionalization route to ketones via the oxidative coupling of arenes with carbon monoxide
por: Levesque, Taleah M., et al.
Publicado: (2020)

Palladium-catalyzed cross-coupling of α-bromocarbonyls and allylic alcohols for the synthesis of α-aryl dicarbonyl compounds
por: Yu, Yang, et al.
Publicado: (2015)

Hypervalent Iodine Reagents in Palladium-Catalyzed Oxidative Cross-Coupling Reactions
por: Shetgaonkar, Samata E., et al.
Publicado: (2020)

Oxidative Cross-Coupling of α-Amino Ketones with Alcohols Enabled by I(2)-Catalyzed C–H Hydroxylation
por: Wang, Yingwei, et al.
Publicado: (2023)

Palladium catalyzed synthesis of indolizines via the carbonylative coupling of bromopyridines, imines and alkynes
por: Roy, Sébastien A., et al.
Publicado: (2020)

Palladium catalyzed carbonylative generation of potent, pyridine-based acylating electrophiles for the functionalization of arenes to ketones
por: Liu, Yi, et al.
Publicado: (2020)

Non-Palladium-Catalyzed Oxidative Coupling Reactions Using Hypervalent Iodine Reagents
por: Shetgaonkar, Samata E., et al.
Publicado: (2022)

Palladium-catalyzed α-arylation of carbonyls in the de novo synthesis of aromatic heterocycles
por: Potukuchi, Harish K., et al.
Publicado: (2015)

Applications of palladium-catalyzed C–N cross-coupling reactions in pharmaceutical compounds
por: Emadi, Reza, et al.
Publicado: (2023)

Palladium-catalyzed/copper-mediated carbon–carbon cross-coupling reaction for synthesis of 6-unsubstituted 2-aryldihydropyrimidines
por: Nishimura, Yoshio, et al.
Publicado: (2022)

Pyridine sulfinates as general nucleophilic coupling partners in palladium-catalyzed cross-coupling reactions with aryl halides
por: Markovic, Tim, et al.
Publicado: (2017)

Palladium-catalyzed cross-coupling reaction of alkenyl aluminums with 2-bromobenzo[b]furans
por: Wen, Chang, et al.
Publicado: (2020)

Palladium catalyzed reductive Heck coupling and its application in total synthesis of (−)-17-nor-excelsinidine
por: Yuan, Lisi, et al.
Publicado: (2021)

Palladium catalyzed radical relay for the oxidative cross-coupling of quinolines
por: Zhao, Xiaorui, et al.
Publicado: (2022)

Synthesis of 3-aryl-2-phosphinoimidazo[1,2-a]pyridine ligands for use in palladium-catalyzed cross-coupling reactions
por: Tran, Ryan Q., et al.
Publicado: (2019)

Aryl acrylonitriles synthesis enabled by palladium-catalyzed α-alkenylation of arylacetonitriles with vinyl halides/triflates
por: Jiang, Yonggang, et al.
Publicado: (2022)

A general strategy for the synthesis of α-trifluoromethyl- and α-perfluoroalkyl-β-lactams via palladium-catalyzed carbonylation
por: Li, Yang, et al.
Publicado: (2021)

Palladium-catalyzed decarbonylative Suzuki–Miyaura cross-coupling of amides by carbon–nitrogen bond activation
por: Zhou, Tongliang, et al.
Publicado: (2019)

Enantioselective rhodium-catalyzed addition of arylboronic acids to N-heteroaryl ketones: synthesis of α-hydroxy acids
por: Zhu, Jinbin, et al.
Publicado: (2023)

Novel synthesis of divergent aryl imidazoles from ketones involving copper-catalyzed α-amination and oxidative C–C bond cleavage
por: Huang, Jiangkun, et al.
Publicado: (2020)

Palladium-Catalyzed Synthesis and Isolation of Functionalized Allylboronic Acids: Selective, Direct Allylboration of Ketones**
por: Raducan, Mihai, et al.
Publicado: (2012)

Palladium-catalyzed dehydrogenative C–H cyclization for isoindolinone synthesis
por: Abe, Masahiro, et al.
Publicado: (2021)

A denitrogenative palladium-catalyzed cascade for regioselective synthesis of fluorenes
por: Fu, Wai Chung, et al.
Publicado: (2019)

Palladium-catalyzed nucleomethylation of alkynes for synthesis of methylated heteroaromatic compounds
por: Yang, Xi, et al.
Publicado: (2022)

Ligand-dependent, palladium-catalyzed stereodivergent synthesis of chiral tetrahydroquinolines
por: Wang, Yue, et al.
Publicado: (2022)

Palladium-catalyzed direct β-arylation of ketones with diaryliodonium salts: a stoichiometric heavy metal-free and user-friendly approach
por: Huang, Zhongxing, et al.
Publicado: (2015)

Cationic palladium(ii)-catalyzed synthesis of substituted pyridines from α,β-unsaturated oxime ethers
por: Yamada, Takahiro, et al.
Publicado: (2022)

Palladium‐Catalyzed Oxidative Synthesis of α‐Acetoxylated Enones from Alkynes
por: Jiang, Tuo, et al.
Publicado: (2016)

Formal aromaticity transfer for palladium-catalyzed coupling between phenols and pyrrolidines/indolines
por: Qiu, Zihang, et al.
Publicado: (2017)

Divergent synthesis of flavones and flavanones from 2′-hydroxydihydrochalcones via palladium(ii)-catalyzed oxidative cyclization
por: Son, Seung Hwan, et al.
Publicado: (2021)

Cobalt-Catalyzed Efficient Asymmetric Hydrogenation of α-Primary Amino Ketones
por: Yang, Huiwen, et al.
Publicado: (2023)

Copper-catalyzed [3+3] annulation of ketones with oxime acetates for the synthesis of pyridines
por: Li, Yilin, et al.
Publicado: (2022)

S(vi) in three-component sulfonamide synthesis: use of sulfuric chloride as a linchpin in palladium-catalyzed Suzuki–Miyaura coupling
por: Wang, Xuefeng, et al.
Publicado: (2021)

Palladium-catalyzed synthesis of 4-sila-4H-benzo[d][1,3]oxazines by intramolecular Hiyama coupling
por: Lee, Donghyeon, et al.
Publicado: (2023)

Sequencing palladium-catalyzed cycloisomerization cascades in a synthesis of the gelsemine core
por: Liang, Guoduan, et al.
Publicado: (2023)

A palladium-catalyzed approach to allenic aromatic ethers and first total synthesis of terricollene A
por: Huang, Chaofan, et al.
Publicado: (2021)

One-Pot Three-Component Coupling Reaction of α-Amino Aryl Ketones, Indoles, and Perbromomethane Under Mild Conditions
por: Chen, De, et al.
Publicado: (2022)

Cyano-borrowing reaction: nickel-catalyzed direct conversion of cyanohydrins and aldehydes/ketones to β-cyano ketone
por: Li, Zhao-Feng, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_m7vb7mgs5gdujs3df23h2q7dil