Cargando…

An integrated strategy for comprehensive characterization of metabolites and metabolic profiles of bufadienolides from Venenum Bufonis in rats

Comprehensive characterization of metabolites and metabolic profiles in plasma has considerable significance in determining the efficacy and safety of traditional Chinese medicine (TCM) in vivo. However, this process is usually hindered by the insufficient characteristic fragments of metabolites, ub...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wei, Wen-Long, Li, Hao-Jv, Yang, Wen-Zhi, Qu, Hua, Li, Zhen-Wei, Yao, Chang-Liang, Hou, Jin-Jun, Wu, Wan-Ying, Guo, De-An
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Xi'an Jiaotong University 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9073132/ https://www.ncbi.nlm.nih.gov/pubmed/35573889 http://dx.doi.org/10.1016/j.jpha.2021.02.003

Ejemplares similares

High Resolution Mass Profile of Bufadienolides and Peptides Combing with Anti-Tumor Cell Screening and Multivariate Analysis for the Quality Evaluation of Bufonis Venenum
por: He, Rongrong, et al.
Publicado: (2019)

Bufadienolides from Venenum Bufonis Inhibit mTOR-Mediated Cyclin D1 and Retinoblastoma Protein Leading to Arrest of Cell Cycle in Cancer Cells
por: Chang, Huamei, et al.
Publicado: (2018)

Effects of Sumsu (Bufonis venenum) Pharmacopuncture Treatment on Depression in Mice
por: Choi, Min-ji, et al.
Publicado: (2014)

Therapeutic effects of Co-Venenum Bufonis Oral Liquid on radiation-induced esophagitis in rats
por: Li, Yang, et al.
Publicado: (2020)

Implementation of a Single Quadrupole Mass Spectrometer for Fingerprint Analysis: Venenum bufonis as a Case Study
por: Wei, Wenlong, et al.
Publicado: (2018)

Study of the Cardiotoxicity of Venenum Bufonis in Rats using an 1H NMR-Based Metabolomics Approach
por: Dong, Ge, et al.
Publicado: (2015)

Comparative Analysis of the Bufonis Venenum by Using TLC, HPLC, and LC-MS for Different Extraction Methods
por: Lee, Hyo-Jae, et al.
Publicado: (2012)

Integrated network pharmacology and molecular docking approaches to reveal the synergistic mechanism of multiple components in Venenum Bufonis for ameliorating heart failure
por: Ren, Wei, et al.
Publicado: (2020)

TXNIP/TRX/NF-κB and MAPK/NF-κB pathways involved in the cardiotoxicity induced by Venenum Bufonis in rats
por: Bi, Qi-rui, et al.
Publicado: (2016)

Apoptotic and anti-metastatic effects of the whole skin of Venenum bufonis in A549 human lung cancer cells
por: PARK, JEONG-SEOK, et al.
Publicado: (2011)

Venenum, Virus, Fear, and Politics
por: Bekerman, Zvi
Publicado: (2020)

Novel Strategies for Solubility and Bioavailability Enhancement of Bufadienolides
por: Shao, Huili, et al.
Publicado: (2021)

Anti-gastric cancer activity in three-dimensional tumor spheroids of bufadienolides
por: Wang, Jixia, et al.
Publicado: (2016)

Endogenous Bufadienolides, Fibrosis and Preeclampsia
por: Reznik, Vitaliy A., et al.
Publicado: (2019)

Lapis bufonis: the growth and decline of a medical superstition.
por: Forbes, T. R.
Publicado: (1972)

NADPH oxidase‐derived reactive oxygen species: Dosis facit venenum
por: Schröder, Katrin
Publicado: (2019)

Bufadienolides originated from toad source and their anti-inflammatory activity
por: Zou, Denglang, et al.
Publicado: (2022)

The Potential Mechanism of Bufadienolide-Like Chemicals on Breast Cancer via Bioinformatics Analysis
por: Zhang, Yingbo, et al.
Publicado: (2019)

New Bufadienolides Isolated from the Roots of Kalanchoe daigremontiana (Crassulaceae)
por: Moniuszko-Szajwaj, Barbara, et al.
Publicado: (2016)

Intramuscular Single-dose Toxicity Test of Bufonis venonum Pharmacopuncture in Sprague-Dawley Rats
por: Lee, Kwang-Ho, et al.
Publicado: (2015)

Evaluation of Bufadienolides as the Main Antitumor Components in Cinobufacin Injection for Liver and Gastric Cancer Therapy
por: Wei, Xiaolu, et al.
Publicado: (2017)

Study of Intravenous Single-Dose Toxicity Test of Bufonis venonum Pharmacopuncture in Sprague-Dawley Rats
por: Kwon, Ki-Rok, et al.
Publicado: (2016)

Novel stereoselective bufadienolides reveal new insights into the requirements for Na(+), K(+)-ATPase inhibition by cardiotonic steroids
por: Tang, Hong-Jin, et al.
Publicado: (2016)

Inhibitory efficacy of bufadienolides on Na(+),K(+)-pump activity versus cell proliferation
por: Xu, Yinfang, et al.
Publicado: (2016)

Electrophysiologic similarities of overdose between digoxin and bufadienolides found in a Chinese aphrodisiac
por: Bressman, Maxwell, et al.
Publicado: (2017)

Bufadienolides of Kalanchoe species: an overview of chemical structure, biological activity and prospects for pharmacological use
por: Kolodziejczyk-Czepas, Joanna, et al.
Publicado: (2017)

Potential Health Risks Posed by Plant-Derived Cumulative Neurotoxic Bufadienolides in South Africa
por: Botha, Christo
Publicado: (2016)

Biological activities of leaf extracts from selected Kalanchoe species and their relationship with bufadienolides content
por: Stefanowicz-Hajduk, Justyna, et al.
Publicado: (2020)

Lipidomics combined with transcriptomic and mass spectrometry imaging analysis of the Asiatic toad (Bufo gargarizans) during metamorphosis and bufadienolide accumulation
por: Sun, Bo, et al.
Publicado: (2022)

Bufadienolides induce p53-mediated apoptosis in esophageal squamous cell carcinoma cells in vitro and in vivo
por: Lin, Shaohuan, et al.
Publicado: (2018)

Molecular Structure-Affinity Relationship of Bufadienolides and Human Serum Albumin In Vitro and Molecular Docking Analysis
por: Zhou, Jing, et al.
Publicado: (2015)

Toad venom-derived bufadienolides and their therapeutic application in prostate cancers: Current status and future directions
por: Ye, Qingmei, et al.
Publicado: (2023)

Enhanced Cytotoxic Effects of Arenite in Combination with Active Bufadienolide Compounds against Human Glioblastoma Cell Line U-87
por: Yuan, Bo, et al.
Publicado: (2022)

Gamabufotalin, a major derivative of bufadienolide, inhibits VEGF-induced angiogenesis by suppressing VEGFR-2 signaling pathway
por: Tang, Ning, et al.
Publicado: (2015)

Telocinobufagin and Marinobufagin Produce Different Effects in LLC-PK1 Cells: A Case of Functional Selectivity of Bufadienolides
por: Amaral, Luciana S., et al.
Publicado: (2018)

Tunable Toxicity of Bufadienolides is Regulated through a Configuration Inversion Catalyzed by a Short‐Chain Dehydrogenase/Reductase
por: Ye, Ge, et al.
Publicado: (2022)

Does the Glucocorticoid Stress Response Make Toads More Toxic? An Experimental Study on the Regulation of Bufadienolide Toxin Synthesis
por: Üveges, B, et al.
Publicado: (2023)

Cytocidal effects of arenobufagin and hellebrigenin, two active bufadienolide compounds, against human glioblastoma cell line U-87
por: Han, Lingyu, et al.
Publicado: (2018)

Bufadienolides from the Skin Secretions of the Neotropical Toad Rhinella alata (Anura: Bufonidae): Antiprotozoal Activity against Trypanosoma cruzi
por: Rodriguez, Candelario, et al.
Publicado: (2021)

Comprehensive Profiling of Mangiferin Metabolites In Vivo and In Vitro Based on the “Drug Metabolite Clusters” Analytical Strategy
por: Zhou, Hongyan, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_3tqmbso357f08muid3lp5topmn