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Facile synthesis of novel dithioacetal–naphthalene derivatives as potential activators for plant resistance induction

In this paper, a series of novel dithioacetal–naphthalenes were designed and synthesized for plant immunity. Their antiviral activities were evaluated against tobacco mosaic virus (TMV) and cucumber mosaic virus (CMV). The results indicated that most compounds exhibited better activity against CMV t...

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Autores principales: Ji, R. J., Shi, W. M., Tian, D. Y., Zhang, G. P., Wang, H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9073188/
https://www.ncbi.nlm.nih.gov/pubmed/35529754
http://dx.doi.org/10.1039/c9ra06843k
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author Ji, R. J.
Shi, W. M.
Tian, D. Y.
Zhang, G. P.
Wang, H.
author_facet Ji, R. J.
Shi, W. M.
Tian, D. Y.
Zhang, G. P.
Wang, H.
author_sort Ji, R. J.
collection PubMed
description In this paper, a series of novel dithioacetal–naphthalenes were designed and synthesized for plant immunity. Their antiviral activities were evaluated against tobacco mosaic virus (TMV) and cucumber mosaic virus (CMV). The results indicated that most compounds exhibited better activity against CMV than against TMV. These dithioacetal derivatives also displayed good bacterial activity against rice bacterial leaf blight. Among them, compound S16 exhibited relatively good anti-CMV, anti-TMV, and antibacterial activity. Structure–activity relationships indicated that introducing the naphthalene moiety enhanced their activities for plant resistance induction. Therefore, the basic motif of compound S16 could be the most promising candidate for further structural optimization to develop a potential activator for plant resistance induction.
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spelling pubmed-90731882022-05-06 Facile synthesis of novel dithioacetal–naphthalene derivatives as potential activators for plant resistance induction Ji, R. J. Shi, W. M. Tian, D. Y. Zhang, G. P. Wang, H. RSC Adv Chemistry In this paper, a series of novel dithioacetal–naphthalenes were designed and synthesized for plant immunity. Their antiviral activities were evaluated against tobacco mosaic virus (TMV) and cucumber mosaic virus (CMV). The results indicated that most compounds exhibited better activity against CMV than against TMV. These dithioacetal derivatives also displayed good bacterial activity against rice bacterial leaf blight. Among them, compound S16 exhibited relatively good anti-CMV, anti-TMV, and antibacterial activity. Structure–activity relationships indicated that introducing the naphthalene moiety enhanced their activities for plant resistance induction. Therefore, the basic motif of compound S16 could be the most promising candidate for further structural optimization to develop a potential activator for plant resistance induction. The Royal Society of Chemistry 2019-10-10 /pmc/articles/PMC9073188/ /pubmed/35529754 http://dx.doi.org/10.1039/c9ra06843k Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Ji, R. J.
Shi, W. M.
Tian, D. Y.
Zhang, G. P.
Wang, H.
Facile synthesis of novel dithioacetal–naphthalene derivatives as potential activators for plant resistance induction
title Facile synthesis of novel dithioacetal–naphthalene derivatives as potential activators for plant resistance induction
title_full Facile synthesis of novel dithioacetal–naphthalene derivatives as potential activators for plant resistance induction
title_fullStr Facile synthesis of novel dithioacetal–naphthalene derivatives as potential activators for plant resistance induction
title_full_unstemmed Facile synthesis of novel dithioacetal–naphthalene derivatives as potential activators for plant resistance induction
title_short Facile synthesis of novel dithioacetal–naphthalene derivatives as potential activators for plant resistance induction
title_sort facile synthesis of novel dithioacetal–naphthalene derivatives as potential activators for plant resistance induction
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9073188/
https://www.ncbi.nlm.nih.gov/pubmed/35529754
http://dx.doi.org/10.1039/c9ra06843k
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